Hiprex for Recurring Urinary Tract Infections
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you are not on antibiotics at the start, but it does not specify about other medications. If you are taking antibiotics, you would need to stop them before joining the trial.
Is Hiprex (methenamine hippurate) safe for humans?
How does the drug Hiprex differ from other treatments for recurring urinary tract infections?
What is the purpose of this trial?
This trial aims to see if Hiprex, which releases bacteria-killing formaldehyde in urine, can help women who frequently get urinary tract infections by reducing their recurrence. Hiprex has been compared with another treatment for preventing these infections, showing similar results.
Research Team
Philippe Zimmern, MD
Principal Investigator
UT Southwestern Medical Center
Eligibility Criteria
This trial is for women aged 50-85 who have had at least two urinary tract infections in the last six months or three in the past year. They must be able to take Hiprex at home and speak English. Women with liver disease, allergies to Hiprex, uncontrolled diabetes, chronic renal failure, or those on antibiotics are excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Methenamine Hippurate (Hiprex™) to measure formaldehyde concentration and evaluate its effects on recurrent urinary tract infections
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Hiprex
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Texas Southwestern Medical Center
Lead Sponsor