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Thyroid Hormone Replacement

Levothyroxine for Heart Failure

Phase 4
Waitlist Available
Research Sponsored by Université de Sherbrooke
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

Study Summary

The purpose of this study is to determine whether levothyroxine supplementation is beneficial in patients with systolic heart failure and subclinical hypothyroidism on the functional class evaluated with a 6 minute walk test.

Eligible Conditions
  • Heart Failure
  • Hypothyroidism

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Performance at the 6 minutes walk test
Secondary outcome measures
Arhythmic (ventricular arrhythmias and supraventricular arrythmias) and ischemic events (myocardial infarction, unstable angina and hospitalization for revascularization)
Difference of activin a measurement
Difference of myostatin measurement
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: LevothyroxineExperimental Treatment1 Intervention
Levothyroxine supplementation

Find a Location

Who is running the clinical trial?

Université de SherbrookeLead Sponsor
292 Previous Clinical Trials
69,401 Total Patients Enrolled
5 Trials studying Heart Failure
629 Patients Enrolled for Heart Failure
Michel Nguyen, MDStudy DirectorCentre de recherche du Centre hospitalier universitaire de Sherbrooke
1 Previous Clinical Trials
43 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism
Paul Farand 2014. "Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02316743.
All > Heart Failure With Preserved Ejection Fraction > Thyroid
~4 spots leftby Apr 2025
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