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furosemide for Hypertension

Phase 4
Waitlist Available
Led By Sheela Barhan, MD
Research Sponsored by Wright State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 14 days after discharge
Awards & highlights

Study Summary

This trial is testing if adding a diuretic to standard treatment for gestational hypertension can lower blood pressure, improve outcomes, and shorten hospital stays.

Eligible Conditions
  • Hypertension

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~number of days of hospital stay from randomization to discharge
This trial's timeline: 3 weeks for screening, Varies for treatment, and number of days of hospital stay from randomization to discharge for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change of Dose for Antihypertensive Therapy
Secondary outcome measures
Breastfeeding Status
Change of Gestational Hypertensive Disorder Symptoms (Diastolic BP)
Change of Gestational Hypertensive Disorder Symptoms (Mean Arterial Pressure)
+3 more

Side effects data

From 2019 Phase 4 trial • 850 Patients • NCT00535925
15%
Acute Myocardial Infarction
9%
stroke
8%
revascularization
1%
major amputation
1%
Hypoglycemia
1%
Hypotension
1%
End Stage Renal Disease
100%
80%
60%
40%
20%
0%
Study treatment Arm
Intensified Therapy
Conventional Therapy

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: labetalol + furosemideExperimental Treatment2 Interventions
labetalol + furosemide
Group II: labetalol onlyActive Control1 Intervention
labetalol only
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Furosemide
FDA approved

Find a Location

Who is running the clinical trial?

Wright State UniversityLead Sponsor
41 Previous Clinical Trials
54,869 Total Patients Enrolled
1 Trials studying Hypertension
144 Patients Enrolled for Hypertension
Sheela Barhan, MDPrincipal InvestigatorWright State University
1 Previous Clinical Trials
105 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Hypertension in PregnancyJournal
Furosemide in Postpartum Management of Severe Preeclampsia: A Randomized Controlled Trial
Veena, P., Lakshmideepthi Perivela, and S. Soundara Raghavan. 2016. “Furosemide in Postpartum Management of Severe Preeclampsia: A Randomized Controlled Trial”. Hypertension in Pregnancy. Informa UK Limited. doi:10.1080/10641955.2016.1239735.
Journal of Obstetrics and GynaecologyJournal
A Randomised Placebo Controlled Trial of Loop Diuretics in Moderate/severe Pre-eclampsia, Following Delivery
MATTHEWS R GORNALL and N J SAUNDERS, G. 1997. “A Randomised Placebo Controlled Trial of Loop Diuretics in Moderate/severe Pre-eclampsia, Following Delivery”. Journal of Obstetrics and Gynaecology. Informa UK Limited. doi:10.1080/01443619750114040.
Obstetrics & GynecologyJournal
Hypertension in Pregnancy
“Hypertension in Pregnancy”. 2013. “Hypertension in Pregnancy”. Obstetrics & Gynecology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/01.aog.0000437382.03963.88.
Obstetrics & GynecologyJournal
First-trimester Prediction of Preeclampsia in Nulliparous Women at Low Risk
Myatt, Leslie, Rebecca G. Clifton, James M. Roberts, Catherine Y. Spong, John C. Hauth, Michael W. Varner, John M. Thorp Jr, et al.. 2012. “First-trimester Prediction of Preeclampsia in Nulliparous Women at Low Risk”. Obstetrics & Gynecology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/aog.0b013e3182571669.
~3 spots leftby Apr 2025
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