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Antiretroviral Combination Therapy

TRIZIVIR + Efavirenz for HIV

Phase 4
Waitlist Available
Research Sponsored by GlaxoSmithKline
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients must be at least 13 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial will compare the effect of two different HIV treatments on viral load.

Who is the study for?
This trial is for HIV-positive individuals aged 13 or older with a viral load of at least 5,000 copies/ml. They must not have used anti-HIV drugs for more than two weeks and agree to reliable birth control methods. Excluded are those with certain health conditions, past drug use, hepatitis in the last six months, or on conflicting medications.Check my eligibility
What is being tested?
The study aims to compare the effects on HIV blood levels between two treatments: one group taking Trizivir (a combination of Abacavir/Lamivudine/Zidovudine) plus Efavirenz and another group taking Trizivir alone.See study design
What are the potential side effects?
Potential side effects may include allergic reactions to medication ingredients, issues affecting liver function like hepatitis, gastrointestinal problems that could interfere with drug absorption, and interactions with other excluded medications.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 13 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

GlaxoSmithKlineLead Sponsor
4,750 Previous Clinical Trials
8,067,052 Total Patients Enrolled

Media Library

Abacavir/Lamivudine/Zidovudine (Antiretroviral Combination Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT00011895 — Phase 4
Human Immunodeficiency Virus Infection Research Study Groups:
Human Immunodeficiency Virus Infection Clinical Trial 2023: Abacavir/Lamivudine/Zidovudine Highlights & Side Effects. Trial Name: NCT00011895 — Phase 4
Abacavir/Lamivudine/Zidovudine (Antiretroviral Combination Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00011895 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what extent can this medical treatment be harmful to individuals?

"Our safety rating for this treatment is a 3 because it has advanced to Phase 4, which demonstrates the efficacy and acceptability of said medication."

Answered by AI

What criteria are needed to be eligible for this investigation?

"This study requires 400 individuals with HIV to take part and they must fall in the age bracket of 13 to 80 years old."

Answered by AI

What is the geographical scope of this research?

"This clinical trial is currently enrolling patients from 42 different sites, with locations ranging from New Orleans to Washington. It may be beneficial for potential participants to choose the clinic closest to them in order to reduce travelling time and costs if they decide to join the study."

Answered by AI

Does the eligibility criteria for this medical experiment extend to those aged 70 and older?

"This clinical trial has set a minimum age of 13 and an upper limit at 80 years old. Meanwhile, there are 108 studies for minors and 352 trials targeting those over 65."

Answered by AI

Are there any vacancies for enrollees in this experiment?

"The clinicaltrial.gov records reflect that this study is not currently in search of participants, despite having been first submitted on February 1st 2001 and last updated June 23rd 2005. However, there are presently 484 other studies actively recruiting patients."

Answered by AI

Who else is applying?

What site did they apply to?
SUNY / Health Sciences Ctr at Brooklyn
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

help myself and others.
PatientReceived no prior treatments
~17 spots leftby Apr 2025