Treatment for Hemorrhoids

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Naval Medical Center Portsmouth, Portsmouth, VA
Hemorrhoids+1 More
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a pain pump can reduce pain after hemorrhoidectomy.

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Eligible Conditions

  • Hemorrhoids

Treatment Effectiveness

Effectiveness Estimate

3 of 3
This is better than 93% of similar trials

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome in patients with Hemorrhoids. Measurement will happen over the course of 1 week.

1 week
VAS pain scales

Trial Safety

Safety Estimate

3 of 3
This is better than 85% of similar trials

Trial Design

2 Treatment Groups

Bupivacaine
1 of 2
Pump device
1 of 2
Active Control
Non-Treatment Group

This trial requires 42 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.

Pump device
Device
One arm will have continuous subcutaneous infusion of normal saline.
Bupivacaine
Device
will receive continuous infusion of bupivacaine

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 week
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 1 week for reporting.

Closest Location

Naval Medical Center Portsmouth - Portsmouth, VA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Patients scheduled for hemorrhoidectomies at NMCP

Patient Q&A Section

What causes pain, postoperative?

"A history of prior pain should be a key initial step in assessing a referral from a general surgeon. Postoperative pain can be substantial, but it has many underlying causes that should be addressed prior to embarking on pain management." - Anonymous Online Contributor

Unverified Answer

Can pain, postoperative be cured?

"Postoperative pain is often the only problem that can't be eliminated with medications. However, with appropriate analgesics, patients may be quite anxious to avoid pain killers because of the fear that pain may return." - Anonymous Online Contributor

Unverified Answer

What are common treatments for pain, postoperative?

"The incidence and prevalence of pain remain significant problems for postoperative patients. There are many treatment options, though no "gold standard" treatment has been found to be effective and safe, with most treatment strategies based on best clinical judgement. The American Association for Orthodontics Practice-Anesthesia and Specialty has created guidelines for the management of pain for postoperative patients." - Anonymous Online Contributor

Unverified Answer

What is pain, postoperative?

"This is an important issue in assessing postoperative pain. It is a complex phenomenon with many factors contributing to a patient's subjective perception of pain over time. Pain intensity in an individual can depend upon many factors and variables. Clinicians' decisions regarding the use of analgesic agents should be based on more than pain intensity alone." - Anonymous Online Contributor

Unverified Answer

How many people get pain, postoperative a year in the United States?

"As of 1999, the national prevalence of pain, postoperative a year was 15% for postoperative back pain, 32% for lower back pain, 12% for thigh pain and 13% for neck pain. These rates varied widely at the local hospital level. Given the prevalence of symptoms and the use of opioids, these rates are worrisome and highlight the need for improved pain monitoring and treatment in the United States." - Anonymous Online Contributor

Unverified Answer

What are the signs of pain, postoperative?

"Almost all of the patients complained of headache following surgery for lumbar disk disease. Postoperative nausea was common in the early postoperative period. Aspiration fever, pneumonia and bronchospasm were also common in the postoperative period. Most of these symptoms were relieved by the introduction of effective analgesics." - Anonymous Online Contributor

Unverified Answer

How serious can pain, postoperative be?

"Results from a recent clinical trial revealed that pain intensity and pain duration, which are important variables in evaluating the severity of pain, vary in patients following surgery. Duration of pain was found to be the most informative variable in assessing the severity of pain." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"Patient education remains an important aspect of treatment. Patients need to be informed, so informed consent is a prerequisite for a successful treatment program. Once treatment begins, patients should be given a clear outline of the expected progress and outcomes in order to maintain their motivation and acceptance of treatment.  Finally, patients should be counseled about the importance of keeping appointments and taking medication at regular intervals." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for pain, postoperative?

"Clinical trial participation would benefit patients and medical professionals alike by providing a means of measuring treatment efficacy against placebo. It could also help identify relevant subgroups of patients for whom specific treatments might be more effective." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets pain, postoperative?

"The number of patients enrolled in the study could have potentially biased data. Because of the retrospective nature of the study, the results need further study." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in treatment for therapeutic use?

"There has not been a good deal of change in treatment and current guidelines for the treatment of patients with postoperative pain. These treatments have improved from the 1960s, but most are still less effective and have more adverse drug reactions, so patients have to take many medications and are more susceptible to complications and side effects. There is no evidence for most common treatments but there are good trials which show that there may be benefit from a combination of oral and parenteral analgesics, NSAIDS, and low dose opioid, paracetamol or acetaminophen. Combination of analgesia and NSAID with paracetamol can reduce pain, nausea and vomiting, and decrease the pain after surgery significantly." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating pain, postoperative?

"There are many discoveries in medical research on treating pain, especially postoperative pain. However, no new discoveries have been found in this subject for this journal." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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