← Back to Search

Prostaglandin E1 Analog

Misoprostol for Uterine Fibroids

Phase 4
Waitlist Available
Led By Magdy Milad, MD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up intra-operative
Awards & highlights

Study Summary

This trial is testing whether a single dose of the medication misoprostol, taken by mouth, can reduce blood loss during surgery to remove fibroid tumors from the uterus.

Eligible Conditions
  • Uterine Fibroids

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from time of surgery completion through discharge from hospital, an expected average period of 3 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and from time of surgery completion through discharge from hospital, an expected average period of 3 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Estimated Intra-operative Blood Loss
Secondary outcome measures
Duration of Procedure
Length of Inpatient Hospitalization
Post-operative Blood Transfusion

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: MisoprostolExperimental Treatment1 Intervention
25 patients undergoing abdominal myomectomy operation will receive two tablets of misoprostol (400 mcg) buccally one hour before the operation.
Group II: PlaceboPlacebo Group1 Intervention
25 patients undergoing abdominal myomectomy operation will receive two tablets of Vitamin B6 (100mg) buccally one hour before the operation.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Misoprostol
2008
Completed Phase 4
~3340

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,586 Previous Clinical Trials
917,204 Total Patients Enrolled
Magdy Milad, MDPrincipal Investigator - Northwestern University, Northwestern Memorial Hopsital
Central DuPage Hospital, Northwestern Lake Forest Hospital, Northwestern Memorial Hospital
Wayne State University School Of Medicine (Medical School)
Mayo Grad School Med/Mayo Fndn (Residency)
3 Previous Clinical Trials
254 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Misoprostol for Reduction of Blood Loss During Fibroid Surgery
Magdy Milad, MD 2014. "Misoprostol for Reduction of Blood Loss During Fibroid Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02209545.
~4 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top