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Diuretic

Loop + Thiazide for Heart Failure

Phase 4
Waitlist Available
Led By Tara Chang, MD, MS
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during hospitalization up to 90 days
Awards & highlights

Study Summary

This trial will compare whether using two types of diuretics or just one will result in shorter hospital stays for heart failure patients.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during hospitalization up to 90 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and during hospitalization up to 90 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hospital length of stay
Secondary outcome measures
Composite of all-cause rehospitalizations, emergency department visits, or death in the 30 days after hospital discharge.

Trial Design

2Treatment groups
Active Control
Group I: Loop + ThiazideActive Control1 Intervention
Participants will receive a loop+thiazide diuretic for up to the first 72 hours of hospitalization. The specific drugs, doses and routes are left to the treating providers.
Group II: Loop onlyActive Control1 Intervention
Participants will receive a loop diuretic for up to the first 72 hours of hospitalization. The specific drug, dose and route are left to the treating providers.

Find a Location

Who is running the clinical trial?

American Heart AssociationOTHER
326 Previous Clinical Trials
4,933,830 Total Patients Enrolled
31 Trials studying Heart Failure
137,779 Patients Enrolled for Heart Failure
Stanford UniversityLead Sponsor
2,393 Previous Clinical Trials
17,341,236 Total Patients Enrolled
18 Trials studying Heart Failure
56,358 Patients Enrolled for Heart Failure
Tara Chang, MD, MSPrincipal InvestigatorStanford University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there current opportunities to enroll in the trial?

"clinicaltrials.gov informs us this clinical trial, which originally posted on December 1st 2022, is not in search of patients currently. However, 701 other trials are actively recruiting at the present moment."

Answered by AI

Could you elaborate on the potential risks of Loop + Thiazide for patients?

"There is ample evidence demonstrating loop thiazide's safety, thus it has been awarded a score of 3."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Comparing Diuretic Strategies in Hospitalized Heart Failure
Tara I-Hsin Chang 2023. "Comparing Diuretic Strategies in Hospitalized Heart Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03999216.
~0 spots leftby Apr 2025
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