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All-blood cardioplegia for Coronary Artery Disease (ABC Trial)

N/A
Waitlist Available
Led By Stacy O'Blenes, MD
Research Sponsored by Pam Trenholm
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 d
Awards & highlights

ABC Trial Summary

This trial is testing whether using all-blood or more diluted cardioplegia during cardiac surgery results in less blood transfusion or better cardiac function.

Eligible Conditions
  • Coronary Artery Disease
  • Valvular Heart Disease

ABC Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 d
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 d for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Blood transfusion
Intra-op diastolic function
Secondary outcome measures
Duration of Ventilation
Fluid balance
Hgb - arrival ICU
+13 more

ABC Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: TreatmentExperimental Treatment1 Intervention
Patients receive all-blood cardiolpegia for myocardial protection during surgery
Group II: ControlActive Control1 Intervention
Patients receive standard 4:1 cardioplegia for myocardial protection during cardiac surgery

Find a Location

Who is running the clinical trial?

Pam TrenholmLead Sponsor
Stacy OBlenesLead Sponsor
Stacy O'Blenes, MDPrincipal InvestigatorDalhousie University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study
Pam Trenholm 2012. "The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01623193.
~4 spots leftby Apr 2025
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