Dietary Supplements for Health

Recruiting at 5 trial locations

Overseen By Chris D'Adamo, Ph.D.

Age: 18+

Sex: Any

Trial Phase: Phase 4

Sponsor: OvationLab

Must not be taking: Statins, H2 blockers, PPIs, bisphosphonates

Disqualifiers: Smoker, Allergies, Pregnant, Chronic conditions, others

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: 8

Duration: 8 weeks

150 Participants Needed

Trial Summary

What is the purpose of this trial?

The primary purpose of this study is to compare the safety and effectiveness of commercially available dietary supplements believed to increase coenzyme Q10 (CoQ10) concentrations. An 8-week, randomized, placebo-controlled clinical trial will be conducted comparing the effectiveness of four commercially available dietary supplements on increasing CoQ10 concentrations and self-reported health outcomes.

Eligibility Criteria

This trial is for individuals interested in improving their health and wellness. Participants should be willing to take dietary supplements or a placebo for 8 weeks. There are no specific inclusion criteria provided, but typically participants must meet certain health standards.

Inclusion Criteria

I am 40 years old or older.

Exclusion Criteria

Participant in a clinical trial in the previous 30 days

I use acid reflux medication daily.

I am currently taking bisphosphonates every day.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive one of four dietary supplements or placebo for 8 weeks to assess CoQ10 concentrations

8 weeks

Baseline and 8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Geranylgeraniol
• Placebo
• Ubiquinol
• Ubiquinol + geranylgeraniol
• Ubiquinone

Trial Overview The study tests the safety and effectiveness of four dietary supplements: Ubiquinol with geranylgeraniol, Ubiquinone alone, Ubiquinol alone, Geranylgeraniol alone, against a placebo. The goal is to see which one increases CoQ10 levels best over an 8-week period.

Participant Groups

Group I: Ubiquinone (NOW CoQ10 200mg) Experimental Treatment 1 Intervention

Group II: Ubiquinol + geranylgeraniol combination (Designs for Health - CoQnol™ 200) Experimental Treatment 1 Intervention

Group III: Ubiquinol (Jarrow Formulas QH-absorb® 200 mg) Experimental Treatment 1 Intervention

Group IV: Geranylgeraniol (Annatto-GG™ 300) Experimental Treatment 1 Intervention

Group V: Placebo Placebo Group 1 Intervention

Who Is Running the Clinical Trial?

OvationLab

Lead Sponsor

Trials

1

Recruited

150+