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Potassium Channel Activator

Diazoxide for Type 2 Diabetes

Phase 4
Waitlist Available
Led By Meredith Hawkins, M.D., M.S.
Research Sponsored by Albert Einstein College of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up final 60 minutes (t=180-240 minutes) of the pancreatic clamp
Awards & highlights

Study Summary

This trial will test whether diazoxide can improve blood sugar control in people with type 2 diabetes by inhibiting the liver's ability to make glucose.

Eligible Conditions
  • Type 2 Diabetes
  • Diabetes
  • High Blood Sugar

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~final 60 minutes (t=180-240 minutes) of the pancreatic clamp
This trial's timeline: 3 weeks for screening, Varies for treatment, and final 60 minutes (t=180-240 minutes) of the pancreatic clamp for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Endogenous Glucose Production (EGP)

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: DiazoxideActive Control1 Intervention
1-2 mg/kg total dose given intravenously during pancreatic clamp study
Group II: PlaceboPlacebo Group1 Intervention
Intravenous normal saline during pancreatic clamp study

Find a Location

Who is running the clinical trial?

National Institutes of Health (NIH)NIH
2,696 Previous Clinical Trials
6,952,570 Total Patients Enrolled
Albert Einstein College of MedicineLead Sponsor
286 Previous Clinical Trials
11,856,971 Total Patients Enrolled
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,358 Previous Clinical Trials
4,315,231 Total Patients Enrolled

Media Library

Diazoxide (Potassium Channel Activator) Clinical Trial Eligibility Overview. Trial Name: NCT01028846 — Phase 4
Type 2 Diabetes Research Study Groups: Diazoxide, Placebo
Type 2 Diabetes Clinical Trial 2023: Diazoxide Highlights & Side Effects. Trial Name: NCT01028846 — Phase 4
Diazoxide (Potassium Channel Activator) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01028846 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants can this clinical trial accommodate?

"At present, this clinical trial has ceased patient recruitment. After first being posted on May 1st 2011 and last updated November 11th 2022, it is no longer searching for participants. For those still interested in taking part in a medical study, there are 1029 trials concerning glucose metabolism disorders and 2 Diazoxide studies that remain open to new volunteers."

Answered by AI

Has the FDA sanctioned Diazoxide for medicinal usage?

"The safety of diazoxide is confidently rated as a 3, due to it having been approved by Phase 4 trials."

Answered by AI

What demographic of participants is most suitable to join this research undertaking?

"Eligible participants must have metabolic abnormalities and be within the range of 21 to 35 years old. This medical research project seeks 10 qualified individuals in total."

Answered by AI

What past investigations have been undertaken with regard to Diazoxide?

"Currently, two trials examining the efficacy of Diazoxide are on-going with no Phase 3 studies in progress. Both research sites are based in Bronx, New york."

Answered by AI

Is the cutoff age for this experiment limited to those 65 or older?

"This clinical study has a restricted age range for enrollment, necessitating that prospective participants are between 21 and 35 years old."

Answered by AI

Are participants able to register for this trial at present?

"Clinicaltrials.gov does not reflect this trial as actively seeking candidates; the study was initially posted on May 1st 2011 and last modified on November 11th 2022, putting it out of date in terms of recruiting participants. However, there are currently 1031 other clinical trials looking for people to join them."

Answered by AI
~1 spots leftby Apr 2025