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Benzodiazepine

clonazepam conversion to clobazam (Onfi) for Epilepsy

Phase 4
Waitlist Available
Led By Steve Chung, MD
Research Sponsored by St. Joseph's Hospital and Medical Center, Phoenix
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 6 - 52 after medication conversion
Awards & highlights

Study Summary

The purpose of the study is to examine the clinical safety, tolerability, and efficacy of clobazam (Onfi) when it replaces the pre-existing clonazepam therapy in patients with refractory epilepsy.

Eligible Conditions
  • Epilepsy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 6 - 52 after medication conversion
This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 6 - 52 after medication conversion for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Efficacy
Secondary outcome measures
Retention
Tolerability

Trial Design

1Treatment groups
Experimental Treatment
Group I: clonazepam conversion to clobazam (Onfi)Experimental Treatment5 Interventions
Subject's clonazepam will be converted to clobazam (Onfi). This is an open label study without placebo control.

Find a Location

Who is running the clinical trial?

St. Joseph's Hospital and Medical Center, PhoenixLead Sponsor
63 Previous Clinical Trials
14,596 Total Patients Enrolled
H. Lundbeck A/SIndustry Sponsor
325 Previous Clinical Trials
77,562 Total Patients Enrolled
3 Trials studying Epilepsy
221 Patients Enrolled for Epilepsy
Steve Chung, MDPrincipal InvestigatorBanner Health Systems

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy
2013. "Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01932502.
All > Lgs Foundation > Epilepsy
~2 spots leftby Apr 2025
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