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Statins

Atorvastatin for Endometriosis

Phase 4
Waitlist Available
Research Sponsored by Penn State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after intervention (7 days)
Awards & highlights

Study Summary

This trial will help us understand how endometriosis affects the lining of blood vessels and raises the risk for disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after intervention (7 days)
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after intervention (7 days) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Nitric Oxide Dependent Vasodilation in the Skin

Side effects data

From 2014 Phase 3 trial • 58 Patients • NCT02084069
3%
Postoperative bleeding
100%
80%
60%
40%
20%
0%
Study treatment Arm
Treatment
Control

Trial Design

1Treatment groups
Experimental Treatment
Group I: AtorvastatinExperimental Treatment1 Intervention
Oral atorvastatin (Lipitor) therapy (10mg/day) for seven days. Atorvastatin acts as a systemic LOX inhibitor.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Atorvastatin
FDA approved

Find a Location

Who is running the clinical trial?

Penn State UniversityLead Sponsor
355 Previous Clinical Trials
125,751 Total Patients Enrolled
4 Trials studying Endometriosis
262 Patients Enrolled for Endometriosis

Media Library

Atorvastatin (Statins) Clinical Trial Eligibility Overview. Trial Name: NCT05331053 — Phase 4
Endometriosis Research Study Groups: Atorvastatin
Endometriosis Clinical Trial 2023: Atorvastatin Highlights & Side Effects. Trial Name: NCT05331053 — Phase 4
Atorvastatin (Statins) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05331053 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals are currently being monitored in this medical experiment?

"Affirmative. According to the details posted on clinicaltrials.gov, this medical trial commenced recruitment on May 1st 2018 and is currently still in progress with an update made as recently as April 8th 2022. The study seeks a total of 10 participants across one specific site location."

Answered by AI

Is eligibility for this medical study restricted to individuals over a certain age?

"The age range of those eligible to partake in this trial is between 18 and 45 years."

Answered by AI

What criteria must be satisfied to qualify for participation in this clinical trial?

"This research project is seeking 10 female patients aged 18-45 with a prior diagnosis of endometrioma. To be eligible, candidates must have had the condition diagnosed by laparoscopy within the last 5 years and reported to researchers."

Answered by AI

Has Atorvastatin obtained government authorization for use?

"The safety of atorvastatin is rated a 3, signifying the trial has reached Phase 4 and the drug has been approved."

Answered by AI

Are participants able to join this clinical research project?

"Yes, the information posted on clinicaltrials.gov demonstrates that recruitment is still ongoing for this trial. It was initially announced on May 1st 2018 and most recently updated April 8th 2022. The study intends to enrol 10 participants at a single site."

Answered by AI

Who else is applying?

What state do they live in?
Utah
Ohio
Texas
How old are they?
18 - 65
What site did they apply to?
The Pennsylvania State University
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
3+
~1 spots leftby Apr 2025