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Antifibrinolytic Agent

Tranexamic acid injection for Swelling

Phase 4
Waitlist Available
Research Sponsored by Consultants in Ophthalmic and Facial Plastics Surgery
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2nd post op visit: post-op day 7 to 10
Awards & highlights

Study Summary

This study is evaluating whether TXA can reduce post-operative bruising.

Eligible Conditions
  • Swelling
  • Bruising

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2nd post op visit: post-op day 7 to 10
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2nd post op visit: post-op day 7 to 10 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Post-operative edema/ecchymosis
Secondary outcome measures
Post-operative complications

Side effects data

From 2021 Phase 3 trial • 1226 Patients • NCT04733157
5%
Vomiting
2%
Dizziness
1%
Nausea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Study Group/Group A_(Tranexamic Acid)
Control Group/Group B_(Placebo)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Tranexamic acid armExperimental Treatment1 Intervention
Eyelid(s) that received tranexamic acid in the local anesthetic
Group II: ControlActive Control1 Intervention
Eyelid(s) that receive local anesthetic without tranexamic acid
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tranexamic acid
FDA approved

Find a Location

Who is running the clinical trial?

Consultants in Ophthalmic and Facial Plastics SurgeryLead Sponsor

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Plastic and Reconstructive SurgeryJournal
The Role of Tranexamic Acid in Plastic Surgery
Rohrich, Rod J., and Min-Jeong Cho. 2018. “The Role of Tranexamic Acid in Plastic Surgery”. Plastic and Reconstructive Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/prs.0000000000003926.
British Journal of SurgeryJournal
Randomized Clinical Trial of Topical Tranexamic Acid After Reduction Mammoplasty
Ausen, K, R Fossmark, O Spigset, and H Pleym. 2015. “Randomized Clinical Trial of Topical Tranexamic Acid After Reduction Mammoplasty”. British Journal of Surgery. Oxford University Press (OUP). doi:10.1002/bjs.9878.
Journal of Bone and Joint SurgeryJournal
Topical Intra-articular Compared with Intravenous Tranexamic Acid to Reduce Blood Loss in Primary Total Knee Replacement
Gomez-Barrena, Enrique, Miguel Ortega-Andreu, Norma G. Padilla-Eguiluz, Hanna Pérez-Chrzanowska, and Reyes Figueredo-Zalve. 2014. “Topical Intra-articular Compared with Intravenous Tranexamic Acid to Reduce Blood Loss in Primary Total Knee Replacement”. Journal of Bone and Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.n.00060.
New England Journal of MedicineJournal
Tranexamic Acid in Patients Undergoing Coronary-artery Surgery
Myles, Paul S., Julian A. Smith, Andrew Forbes, Brendan Silbert, Mohandas Jayarajah, Thomas Painter, D. James Cooper, et al.. 2017. “Tranexamic Acid in Patients Undergoing Coronary-artery Surgery”. New England Journal of Medicine. Massachusetts Medical Society. doi:10.1056/nejmoa1606424.
~14 spots leftby Apr 2025
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