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Insulin

0% Bolus Insulin Correction for Type 1 Diabetes (FIT Trial)

Phase 4
Waitlist Available
Led By Ronnie Aronson, MD
Research Sponsored by LMC Diabetes & Endocrinology Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Male or female
Clinical diagnosis of presumed autoimmune T1D
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 147 days
Awards & highlights

FIT Trial Summary

The overall objective of this study is to investigate the glycemic response of a 0%, 50%, 100% and 150% bolus insulin correction (based on personal insulin correction factor) of post-exercise hyperglycemia in physically active adults with type 1 diabetes (T1D) using multiple daily injections (MDI) in a controlled, but clinically representative, experimental setting.

Eligible Conditions
  • Type 1 Diabetes

FIT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

FIT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~147 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 147 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Reduction In Plasma Glucose (YSI)
Secondary outcome measures
Investigate Glycemic Response of a 0%, 50%, 100% and 150% Bolus Insulin Correction of Post-exercise Hyperglycemia Compared to no Bolus Insulin Correction

FIT Trial Design

4Treatment groups
Active Control
Group I: 0% Bolus Insulin CorrectionActive Control1 Intervention
0% Bolus Insulin Correction
Group II: 50% Bolus Insulin CorrectionActive Control1 Intervention
50% Bolus Insulin Correction
Group III: 100% Bolus Insulin CorrectionActive Control1 Intervention
100% Bolus Insulin Correction
Group IV: 150% Bolus Insulin CorrectionActive Control1 Intervention
150% Bolus Insulin Correction

Find a Location

Who is running the clinical trial?

LMC Diabetes & Endocrinology Ltd.Lead Sponsor
16 Previous Clinical Trials
22,865 Total Patients Enrolled
SanofiIndustry Sponsor
2,161 Previous Clinical Trials
3,512,021 Total Patients Enrolled
Ronnie Aronson, MDPrincipal InvestigatorLMC Diabetes & Endocrinology
7 Previous Clinical Trials
10,433 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Optimal Insulin Correction Factor in Post- High Intensity Exercise Hyperglycemia in Adults With Type 1 Diabetes (FIT)
2016. "Optimal Insulin Correction Factor in Post- High Intensity Exercise Hyperglycemia in Adults With Type 1 Diabetes (FIT)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03057470.
All > Type 1 Diabetes
~2 spots leftby Apr 2025
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