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Antiseptic

Decolonization for Infections (PROTECT Trial)

Phase 4
Waitlist Available
Led By Susan Huang, MD MPH
Research Sponsored by University of California, Irvine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up once in baseline and once at end-intervention (month 15-18 of intervention period)
Awards & highlights

PROTECT Trial Summary

This trial will compare two methods of preventing infection in nursing homes: routine chlorhexidine bathing and periodic use of nasal antiseptics. The goal is to see if these methods can reduce hospitalizations, antibiotic use, and multi-drug resistant organism (MDRO) prevalence.

Eligible Conditions
  • Infection
  • Hospitalizations

PROTECT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~once in baseline and once at end-intervention (month 15-18 of intervention period)
This trial's timeline: 3 weeks for screening, Varies for treatment, and once in baseline and once at end-intervention (month 15-18 of intervention period) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hospital Transfers Due to Infection
Secondary outcome measures
All Hospital Transfers
Other outcome measures
All Hospital Transfers in Long Stay and Short Stay Subsets (Secondary Manuscript, Added by Steering Committee Decision on 3/22/2017)
Emergency Department Transfers Due to Infection (Secondary Manuscript, Added by Steering Committee Decision on 3/22/2017)
Hospital Transfers Due to Infection in Long Stay and Short Stay Subsets (Secondary Manuscript, Added by Steering Committee Decision on 3/22/2017)
+1 more

PROTECT Trial Design

2Treatment groups
Active Control
Group I: DecolonizationActive Control2 Interventions
Nursing homes assigned to this arm will perform decolonization using topical antiseptic products.
Group II: Routine BathingActive Control1 Intervention
Routine bathing per facility protocol.

Find a Location

Who is running the clinical trial?

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterOTHER
101 Previous Clinical Trials
32,349 Total Patients Enrolled
4 Trials studying Infections
1,036 Patients Enrolled for Infections
Agency for Healthcare Research and Quality (AHRQ)FED
399 Previous Clinical Trials
6,808,396 Total Patients Enrolled
21 Trials studying Infections
1,077,771 Patients Enrolled for Infections
University of Massachusetts, AmherstOTHER
78 Previous Clinical Trials
453,820 Total Patients Enrolled
4 Trials studying Infections
2,963 Patients Enrolled for Infections

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many healthcare facilities are facilitating this clinical trial?

"Currently, 28 medical sites are hosting this trial. Examples of these locations include Capistrano Beach, Long Beach and Bellflower. It is recommended that participants select the closest site to them in order to minimise travel requirements associated with the study."

Answered by AI

What is the most common purpose of Decolonization?

"Decolonization is a process that can be employed to treat antisepsis, as well as disinfection of wounds, pharyngitis, and pressure sores."

Answered by AI

Are there any potential risks associated with Decolonization initiatives?

"Our scientists have assigned Decolonization a score of 3, which is the highest possible given that this treatment has already been approved by regulatory authorities."

Answered by AI

What is the participant capacity of this clinical research study?

"Unfortunately, this clinical trial is not currently taking on any new patients. First posted in April 2017 and most recently updated in June 2022, other studies are available with 800 trials related to infection presently enrolling participants as well as 28 Decolonization-focused studies that require volunteers."

Answered by AI

Has Decolonization been investigated in other clinical experiments?

"Currently, 28 Decolonization research projects are in progress. Of those studies, 5 have advanced to Phase 3 trials. There is a concentration of clinical sites located in Greenville South carolina but the investigation spans 121 different locations across the US."

Answered by AI

Is there a call for volunteers to participate in this research endeavor?

"Evidently, this clinical trial is no longer accepting applicants as reported on clinicaltrials.gov; the initial posting was 4/3/2017 and it has been modified for the last time on 6/7/2022. However, there are 828 other trials that have open recruitment at present."

Answered by AI

Who else is applying?

What state do they live in?
California
What site did they apply to?
Capistrano Beach Care Center
Park Regency Care Center
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

My father died due to acquiring an infection during hospitalization, I want to help reduce incidences like this.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
Susan Huang 2017. "Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03118232.
~1744 spots leftby Apr 2025
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