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Pain injection for Cerebral Palsy

Phase 4

Waitlist Available

Led By Rachel M Thompson, MD

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up expected 3-4 days

Awards & highlights

Study Summary

This trial is testing whether or not a pain injection can help reduce pain in pediatric patients with cerebral palsy who are undergoing major hip surgery.

Eligible Conditions

Cerebral Palsy
Hip Dysplasia
Postoperative Pain

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ expected 3-4 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~expected 3-4 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and expected 3-4 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Opioid consumption

Secondary outcome measures

Hospital length of stay

Parent satisfaction

Pain

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Pain injectionActive Control1 Intervention

This group will be injected with a cocktail totaling 40mL (20mL on each side) that will be composed of ropivicaine 2mg/mL (3mg/kg), epinephrine 1mg/mL (0.5mg), ketorolac 30mg/mL (0.5mg/kg).

Group II: Normal salinePlacebo Group1 Intervention

The control group will receive an injection of 40mL of 0.9% sodium chloride solution.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

University of California, Los AngelesLead Sponsor

1,526 Previous Clinical Trials

10,275,870 Total Patients Enrolled

2 Trials studying Cerebral Palsy

120 Patients Enrolled for Cerebral Palsy

Northwestern UniversityOTHER

1,584 Previous Clinical Trials

917,731 Total Patients Enrolled

4 Trials studying Cerebral Palsy

495 Patients Enrolled for Cerebral Palsy

Rachel M Thompson, MDPrincipal InvestigatorUniversity of California, Los Angeles

3 Previous Clinical Trials

180 Total Patients Enrolled

1 Trials studying Cerebral Palsy

90 Patients Enrolled for Cerebral Palsy

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants have been accepted into this clinical experiment?

"Affirmative. The entry on clinicaltrials.gov reveals that this medical trial has reopened and is currently seeking enrolment for 90 participants across 4 institutes. This research study was first posted to the website on December 1, 2019 with its last edit occurring October 18, 2022."

Answered by AI

Have any other experiments evaluated the efficacy of pain injection therapies?

"At this time, 121 clinical trials related to Pain injection are active with 26 in Phase 3. Boston is a popular destination for research on the subject, yet there remain 173 sites around the world studying it."

Answered by AI

What formal approval has been given for using injection as a form of pain relief?

"There is ample evidence of safety for the Pain injection, so it has been ranked a 3. This Phase 4 trial demonstrates that this treatment already meets all requirements for approval."

Answered by AI

Are there available vacancies in this experiment for participants?

"Data hosted on clinicaltrials.gov confirms that recruitment for this trial is still open. The experiment was first posted to the website in December 2019 and has since been refreshed as recently as October 18th 2022."

Answered by AI

What ailments can be alleviated through the administration of pain injections?

"Pain injection is a common solution for unresponsive bradycardia and can also be employed to remedy miosis disorder, pupillary resistance and labour pain."

Answered by AI

Recent research and studies

Journal of Bone and Joint SurgeryJournal

Efficacy of Surgical-site, Multimodal Drug Injection Following Operative Management of Femoral Fractures

Koehler, Daniel, J. Lawrence Marsh, Matthew Karam, Catherine Fruehling, and Michael Willey. 2017. “Efficacy of Surgical-site, Multimodal Drug Injection Following Operative Management of Femoral Fractures”. Journal of Bone and Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.16.00733.

PediatricsJournal

Persistent Opioid Use Among Pediatric Patients After Surgery

Harbaugh, Calista M., Jay S. Lee, Hsou Mei Hu, Sean Esteban McCabe, Terri Voepel-Lewis, Michael J. Englesbe, Chad M. Brummett, and Jennifer F. Waljee. 2018. “Persistent Opioid Use Among Pediatric Patients After Surgery”. Pediatrics. American Academy of Pediatrics (AAP). doi:10.1542/peds.2017-2439.

The Journal of Bone & Joint SurgeryJournal

A Multimodal Analgesia Protocol for Total Knee Arthroplasty

Vendittoli, Pascal-André, Patrice Makinen, Pierre Drolet, Martin Lavigne, Michel Fallaha, Marie-Claude Guertin, and France Varin. 2006. “A Multimodal Analgesia Protocol for Total Knee Arthroplasty”. The Journal of Bone & Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.e.00173.

clinicaltrials.govStudy