← Back to Search

1 Week Levetiracetam for Brain Cancer

Phase 4
Waitlist Available
Led By Maryam Rahman, MS, MD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 6 weeks
Awards & highlights

Study Summary

The purpose of this study is to see if there are any differences in patient reported neurotoxicity between patients who receive Levetiracetam tablets for one week after surgery to remove a brain tumor versus those who receive Levetiracetam tablets for six weeks after surgery. Specifically, we will see if one group has less side effects than the other, and whether or not one group has more seizures than the other.

Eligible Conditions
  • Brain Cancer
  • Seizures
  • Brain Tumor
  • Brain Metastases

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Neurotoxicity Scale Scores

Side effects data

From 2006 Phase 4 trial • 251 Patients • NCT00160654
30%
Somnolence
14%
Dizziness
6%
Sedation
6%
Fatigue
6%
Headache
6%
Nausea
2%
Convulsion
1%
Grand mal convulsion
100%
80%
60%
40%
20%
0%
Study treatment Arm
Levetiracetam

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 1 Week LevetiracetamExperimental Treatment1 Intervention
Levetiracetam taken by mouth at a daily dose of 1000 mg for one week.
Group II: 6 Week LevetiracetamActive Control1 Intervention
Levetiracetam taken by mouth at a daily dose of 1000 mg for six weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Levetiracetam
2017
Completed Phase 4
~3990

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor
1,345 Previous Clinical Trials
718,236 Total Patients Enrolled
Maryam Rahman, MS, MDPrincipal InvestigatorUniversity of Florida

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
2015. "1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02334722.
~8 spots leftby May 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top