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Anti-tumor antibiotic

1-drug Therapy for Appendicitis

Phase 4

Waitlist Available

Led By Justin Lee, MD

Research Sponsored by Phoenix Children's Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 30 days

Awards & highlights

Study Summary

This trial will compare the two most commonly used antibiotic regimens for perforated appendicitis to see which is better.

Eligible Conditions

Appendicitis
Infections

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants With a Postoperative Intra-abdominal Abscess

Secondary outcome measures

Number of Participants With Postoperative Surgical Site Infection

Number of Participants With a Postoperative Readmission

Side effects data

From 2023 Phase 4 trial • 162 Patients • NCT03289351

Perioperative Redness/Edema

100%

80%

60%

40%

20%

Study treatment Arm

2-drug Therapy

1-drug Therapy

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: 1-drug TherapyExperimental Treatment1 Intervention

piperacillin-tazobactam

Group II: 2-drug TherapyActive Control1 Intervention

ceftriaxone/metronidazole

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Piperacillin

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Phoenix Children's HospitalLead Sponsor

73 Previous Clinical Trials

5,013,826 Total Patients Enrolled

1 Trials studying Appendicitis

7 Patients Enrolled for Appendicitis

Justin Lee, MDPrincipal InvestigatorPhoenix Childrens Hospital

2 Previous Clinical Trials

188 Total Patients Enrolled

Media Library

Piperacillin (Anti-tumor antibiotic) Clinical Trial Eligibility Overview. Trial Name: NCT03289351 — Phase 4

Appendicitis Research Study Groups: 2-drug Therapy, 1-drug Therapy

Appendicitis Clinical Trial 2023: Piperacillin Highlights & Side Effects. Trial Name: NCT03289351 — Phase 4

Piperacillin (Anti-tumor antibiotic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03289351 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what medical afflictions is piperacillin-tazobactam typically prescribed?

"Piperacillin-tazobactam is a potent antibiotic that can be prescribed to treat urinary tract infection and other conditions, like nosocomial pneumonia, lower respiratory tract infections (LRTI), and bacterial illnesses."

Answered by AI

What is the population size of the individuals taking part in this experiment?

"This experiment is no longer taking on new patients. Initially posted on May 22nd 2017, the last edit was made April 22nd 2022. If you're trying to find other studies pertaining to appendicitis and piperacillin-tazobactam there are 32 and 18 open clinical trials at this time respectively."

Answered by AI

Is there capacity to accept more participants in this clinical trial?

"All information detailed on clinicaltrials.gov suggests that this particular trial is no longer recruiting patients as of April 22nd, 2022. The original post date was May 22nd 2017. Fortunately there are 50 other studies in progress seeking patient recruitment at the present time."

Answered by AI

Has the Federal Drug Administration issued their blessing for piperacillin-tazobactam?

"There is ample evidence supporting piperacillin-tazobactam's safety, which resulted in a score of 3. This drug has been accepted for use by regulatory bodies and completed Phase 4 trials with successful outcomes."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis

2017. "Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03289351.