Microplegia for Aortic Valve Stenosis

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Aortic Valve Stenosis+4 MoreMicroplegic Solution No. 1 - Drug
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial will test whether undiluted microplegia reduces transfusion rates in patients after planned heart surgery, as compared to standard 4:1 cardioplegia.

Eligible Conditions
  • Aortic Valve Stenosis
  • Mitral Valve Disease

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 30 days

30 days
Effects of Microplegia on overall morbidity and mortality during peri-operative period
Microplegia results in less peri-operative transfusions

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Microplegia
1 of 2
Cardioplegia
1 of 2

Active Control

314 Total Participants · 2 Treatment Groups

Primary Treatment: Microplegia · No Placebo Group · Phase 4

Microplegia
Drug
ActiveComparator Group · 1 Intervention: Microplegic Solution No. 1 · Intervention Types: Drug
Cardioplegia
Drug
ActiveComparator Group · 1 Intervention: Cardioplegia Solution · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 30 days

Who is running the clinical trial?

Washington University School of MedicineLead Sponsor
1,805 Previous Clinical Trials
2,278,389 Total Patients Enrolled
3 Trials studying Aortic Valve Stenosis
31 Patients Enrolled for Aortic Valve Stenosis
Quest Medical, IncUNKNOWN
Spencer J Melby, MDPrincipal InvestigatorWashington University School of Medicine

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

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References