Treatment for Pregnant State

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Northwestern Memorial Hospital and Prentice Women's Hospital, Chicago, IL
Pregnant State+2 More
Eligibility
18+
Female
Eligible conditions
Select

Study Summary

This study is evaluating whether metoclopramide reduces gastric volume in women who are scheduled for cesarean delivery.

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Eligible Conditions

  • Pregnant State
  • Aspiration
  • Cesarean Sections

Treatment Effectiveness

Effectiveness Estimate

3 of 3
This is better than 93% of similar trials

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 2 secondary outcomes in patients with Pregnant State. Measurement will happen over the course of 24 hours.

24 hours
Incidence (number of events) of nausea and vomiting
30 minutes after administration of study drug
Change in gastric volume (mL)
48 hours
Adverse events

Trial Safety

Safety Estimate

3 of 3
This is better than 85% of similar trials

Trial Design

2 Treatment Groups

Group 1 Study Drug Metoclopramide
1 of 2
Group 2 Study Drug Placebo
1 of 2
Active Control
Non-Treatment Group

This trial requires 72 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.

Group 1 Study Drug Metoclopramide
Drug
Intravenous administration of 10 mg metoclopramide
Group 2 Study Drug Placebo
Drug
Intravenous administration of sterile normal saline

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 48 hours
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 48 hours for reporting.

Who is running the study

Principal Investigator
J. B.
Jennifer Banayan, Principal Investigator
Northwestern University

Closest Location

Northwestern Memorial Hospital and Prentice Women's Hospital - Chicago, IL

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Healthy (ASA Physical Status 2)
Age >18 years old
Non-obese (BMI <40 kg/m2)
Age >18 years
Term (>37 week)
Non-laboring parturient
Single gestation
Scheduled for a cesarean delivery and NPO

Patient Q&A Section

What are the signs of pregnant state?

"Signs of pregnancy include weight gain, headache, nausea and itching. There may be some signs that can be indicative of ectopic pregnancy, however most are non-specific and might be due to other conditions. Symptoms of hypertension in pregnancy can include swelling in ankles and dizziness. Symptoms of diabetes in pregnancy can include abdominal pain, feeling full, and tiredness.\n" - Anonymous Online Contributor

Unverified Answer

Can pregnant state be cured?

"Early diagnosis and the use of adequate treatment (antibiotics) can prevent serious consequences. Therefore, pregnant women should take advantage of early identification of symptoms so that early treatment can be started." - Anonymous Online Contributor

Unverified Answer

How many people get pregnant state a year in the United States?

"The U.S. in 2002 (and the year ahead) is projected to have 21 million new pregnancies. Only a minority of these (40%) will be unplanned. The rate of unintended pregnancy in the United States will decrease from 10% in 1993, but will remain above the replacement level of 3.6%." - Anonymous Online Contributor

Unverified Answer

What is pregnant state?

"Pregnancy is a stressful period in the lives of most individuals and the level of anxiety and depressive symptomatology are influenced by various stressors that are unique to the pregnant state, as well as preexisting personality tendencies or disposition. Most of the anxiety disorders and depressive symptoms experienced by the individual during the pregnant state are not related to postpartum symptoms." - Anonymous Online Contributor

Unverified Answer

What are common treatments for pregnant state?

"The majority of medications given to women during pregnancy are indicated for their utility to fetal well-being. Those medications that are not effective, although indicated for fetal or maternal health, pose a significant hazard to the fetus and are considered contraindicated.\n" - Anonymous Online Contributor

Unverified Answer

What causes pregnant state?

"The most common causes of pregnant state are: high BMI, obesity, diabetes, smoking, and alcohol abuse of an pregnant women, and she is getting younger." - Anonymous Online Contributor

Unverified Answer

Is treatment safe for people?

"There is no increased risk of cancer or pregnancy-related complications when women and their partners use the most active chemoprophylaxis agents for secondary prevention and secondary treatment. The risk of pregnancy loss is significantly greater in those women who smoke, are African American, or use a higher dose regime of these agents." - Anonymous Online Contributor

Unverified Answer

Is treatment typically used in combination with any other treatments?

"A significant percentage of women with breast cancer are treated with other treatments in combination with the estrogen-receptor blockade, including chemotherapy, targeted agents, and the trastuzumab. Although the benefits of these combinations seem to outweigh the harms, the optimal treatment choice and sequence of agents in all specific situations remains unclear. Randomised clinical trials, as well as individualised treatment strategies, should be employed in order to evaluate and refine management strategies for women with this disease." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating pregnant state?

"Treatment options have improved since the 1960s, and further progress is still needed. Randomized controlled studies showing differences between treatment options may help clarify the role of the therapeutic regimens for specific cases. More research is needed to ascertain and develop effective treatment options for Pregnant patients with Parkinson's disease. The first step may be developing and evaluating new treatments." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"Most patients who participated in this study were in remission from RA at enrollment, but they were still working with a physician for treatment that included NSAIDS in an increasing proportion of cases. There was some interest in the potential for patient use of alternative, more patient-directed approaches to managing RA." - Anonymous Online Contributor

Unverified Answer

Has treatment proven to be more effective than a placebo?

"Currently available and promising antiepileptic drugs as monotherapy and, particularly, when combined with another antiepileptic drug, are very effective in resolving status epilepticus. Clinical trials provide evidence of the possible efficacy of a combination of antiepileptic drug treatment for status epilepticus. For patients with epilepsy, the combination of a single antiepileptic drug treatment with a placebo is not a proven option. The most feasible approach is that in which patients are matched appropriately by evaluating their epilepsy phenotype and then administering the recommended medication." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for pregnant state?

"The health care provider making the final decision regarding whether to start, continue, or discontinue any trial during pregnancy should weigh whether or not there is a theoretical or proven benefit of the intervention against the risks. The information available for evaluation of harms and benefits may be limited and thus may not lead to an appropriate decision." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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