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Local Anesthetic

Chloroprocaine Injection [Clorotekal] for Spinal Anesthesia (CLIMB Trial)

Phase 4
Waitlist Available
Led By Brandon M Togioka, MD
Research Sponsored by Oregon Health and Science University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hours
Awards & highlights

CLIMB Trial Summary

This study is evaluating whether a new medication may be more effective than the current standard for spinal anesthesia during labor and delivery.

CLIMB Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Motor block-interval assessment
Secondary outcome measures
Bladder Catheterization
Motor block-patient report
Phase 1 Post-Anesthesia Care Unit time
+2 more
Other outcome measures
Opioid consumption
Peak block sensory level

CLIMB Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ChloroprocaineExperimental Treatment1 Intervention
50 mg of 1% spinal chloroprocaine (5 mL) injected into the intrathecal space over approximately 5 seconds once prior to the start of surgery
Group II: BupivacaineActive Control1 Intervention
10.5 mg of spinal hyperbaric bupivacaine (1.4 mL of 0.75% bupivacaine hydrochloride in 8.25% dextrose) injected into the intrathecal space over approximately 5 seconds once prior to the start of surgery

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor
974 Previous Clinical Trials
7,385,885 Total Patients Enrolled
B. Braun Medical Inc.Industry Sponsor
17 Previous Clinical Trials
571 Total Patients Enrolled
Brandon M Togioka, MDPrincipal Investigator - Oregon Health and Science University
Oregon Health and Science University
7 Previous Clinical Trials
1,025 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
Brandon M Togioka 2019. "Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03967288.
~0 spots leftby Jun 2024
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