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Local Anesthetic

Group 2 for Post-Thorascopic Surgical Pain

Phase 4
Waitlist Available
Research Sponsored by Cedars-Sinai Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18 - 80 years old of either gender, scheduled for unilateral VATS procedure with Dr. McKenna for resection of lung tumor.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 72 hours post operatively
Awards & highlights

Study Summary

The proposed study is a randomized, double-blinded, non-placebo-controlled evaluation of the effect of the addition of dexamethasone to intraoperative intercostal nerve block bupivicaine solutions on the duration of pain relief and post operative pulmonary function.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~72 hours post operatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and 72 hours post operatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Post operative pain

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Group 2Active Control1 Intervention
an intercostal nerve block with a solution consisting of 0.46% bupivicaine (19.5 ml of 0.5% bupivicaine + .5ml .4% dexamethasone)
Group II: Group 1Placebo Group1 Intervention
an intercostal nerve block with a solution consisting of 0.46% bupivicaine (19.5 ml of 0.5% bupivicaine + .5ml normal saline)

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Who is running the clinical trial?

Cedars-Sinai Medical CenterLead Sponsor
499 Previous Clinical Trials
164,807 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The Effect of Dexamethasone on the Duration and Functionality of Bupivacaine Intercostal Nerve Blockade
dermot Maher 2013. "The Effect of Dexamethasone on the Duration and Functionality of Bupivacaine Intercostal Nerve Blockade". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02005575.
All > Exparel
~4 spots leftby Apr 2025
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