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Antiplatelet Agent

Aspirin for Platelet Disorder

Phase 4
Waitlist Available
Led By Kenneth E Thummel, Ph.D.
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up single 9 am blood sample on day 3 of study
Awards & highlights

Study Summary

This trial will look at how different levels of n-3 PUFAs (found in fish oils) affect platelet aggregation in American Indian and Alaska Native people, and whether this is affected by variation in genes.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~single 9 am blood sample on day 3 of study
This trial's timeline: 3 weeks for screening, Varies for treatment, and single 9 am blood sample on day 3 of study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
PFA-100 Platelet Aggregation Test
Secondary outcome measures
Platelet 20-HETE concentration
Platelet TBX2 concentration

Trial Design

1Treatment groups
Experimental Treatment
Group I: Low and High n-3 PUFAExperimental Treatment1 Intervention
Individuals with low or high n-3 PUFA RBC concentration will be given aspirin (81 mg of aspirin once a day, for 6 days)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Aspirin
2014
Completed Phase 4
~55580

Find a Location

Who is running the clinical trial?

University of WashingtonLead Sponsor
1,738 Previous Clinical Trials
1,844,225 Total Patients Enrolled
Southcentral FoundationOTHER
6 Previous Clinical Trials
6,548 Total Patients Enrolled
Oregon Health and Science UniversityOTHER
973 Previous Clinical Trials
6,845,903 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has a similar experiment of this magnitude been conducted before?

"Since its initial trial in 2005, sponsored by Abbott and involving 15480 participants, Aspirin has been studied extensively. It was approved for Phase 4 drug use shortly after that first study and currently there are 167 active trials which span 57 countries and 1398 cities."

Answered by AI

What conditions typically warrant the use of Aspirin?

"Percutaneous coronary intervention (PCI) is typically treated with Aspirin, although it can also help reduce inflammation and pain associated with dental procedures or neck discomfort."

Answered by AI

Is the usage of Aspirin for medical purposes associated with any adverse outcomes?

"Aspirin has gone through rigorous safety testing over multiple phases, so its security is rated highly at a 3 on our scale."

Answered by AI

Are new participants being accepted for this research project?

"Unfortunately, this medical trial is not presently recruiting. Although it was initially posted on August 1st 2016 and last updated June 9th 2022, other options are available for those looking to participate in clinical trials related to platelet function or Aspirin; as of now there are two studies open with the former and one hundred sixty-seven associated with the latter."

Answered by AI

To what extent has this clinical trial been embraced by patients?

"Unfortunately, this clinical trial has reached its recruitment limit and is no longer accepting applicants. Initially posted on August 1st 2016 before being updated to June 9th 2022, the research team are now focusing their attention elsewhere. Alternately, there are two trials exploring platelet function plus 167 studies centred around Aspirin that have open slots for volunteers."

Answered by AI

What prior studies have been conducted utilizing Aspirin as a therapeutic agent?

"In 2005, Clinical Trial Service Unit at NDPH of the University Oxford began their exploration into aspirin. Since then, 511 clinical trials have been concluded while 167 studies remain active and recruiting participants in Portland Oregon and other locations."

Answered by AI
~15 spots leftby Apr 2025