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Young females (21-30 years old) for Lip Aging

Phase 4

Waitlist Available

Led By Dieter Manstein, MD, PhD

Research Sponsored by Dieter Manstein, MD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up d1 and d14

Awards & highlights

Study Summary

This trial will compare changes in lips and skin before and after lip filler treatment in two different age groups to learn more about the effects of aging and lip filler treatment.

Eligible Conditions

Lip Aging
Lip
Lip Filler

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ d1 and d14

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~d1 and d14

This trial's timeline: 3 weeks for screening, Varies for treatment, and d1 and d14 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Lip Vessel's Thickness

Secondary outcome measures

Lip Fullness Measurement (Measures the Increase of Lip's Size After the Procedure)

Wong-Baker FACES Pain Rating Scale

Other outcome measures

Change in Lip color

Change in Lip texture

Change in Lip volume

Side effects data

From 2022 Phase 4 trial • 37 Patients • NCT04839692

Asymmetry

100%

80%

60%

40%

20%

Study treatment Arm

Young Females (21-30 Years Old)

Post Menopausal Females

Trial Design

2Treatment groups

Experimental Treatment

Group I: post menopausal femalesExperimental Treatment1 Intervention

post menopausal females from all phototypes who have thin or moderately thick lips

Group II: Young females (21-30 years old)Experimental Treatment1 Intervention

young healthy females (21-30 years old) from all phototypes who have thin or moderately thick lips

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Hyaluronic acid filler

2021

Completed Phase 4

~60

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Dieter Manstein, MDLead Sponsor

Dieter Manstein, MD, PhDPrincipal InvestigatorMassachusetts General Hospital

5 Previous Clinical Trials

89 Total Patients Enrolled

Neera Nathan, MD, MSHSPrincipal InvestigatorMassachusetts General Hospital

3 Previous Clinical Trials

54 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In what medical conditions is this therapeutic approach commonly used?

"This medication is typically used to manage dermal discomfort, but has been known to assist patients with osteoarthritis (OA), skin abrasion, and dermatological issues."

Answered by AI

Could you provide information on the other trials that have analyzed this therapeutic approach?

"Currently, 16 medical trials are ongoing to assess the efficacy of this treatment. 4 of those clinical experiments have reached Phase 3. While Morgantown, West virginia hosts several studies for it, there are 31 other locations participating in these investigations."

Answered by AI

Are there any additional openings for potential participants in this experiment?

"This investigation is no longer enrolling participants. Initially posted on July 7th 2021, the trial was last adjusted 8/30/2022. For those searching for analogous studies, there are currently 6 clinical trials targeting lip and 16 trials actively seeking patients who will receive this treatment."

Answered by AI

What is the magnitude of people taking part in this medical investigation?

"As of now, this clinical trial is not seeking participants. Initially posted on July 7th 2021 and last updated August 30th 2022, it appears that several other trials for lip related treatments are actively recruiting patients - 6 to be exact. Additionally, there are 16 studies currently searching for potential candidates for a similar treatment."

Answered by AI

Has this particular therapy been sanctioned by the FDA?

"As this is a Phase 4 trial, which implies that the treatment has already been approved, we have assigned it an efficacy score of 3 on our rating scale."

Answered by AI

Recent research and studies

British Journal of DermatologyJournal

The Senile Epidermis: Environmental Influences on Skin Ageing and Cutaneous Carcinogenesis

ROGERS, G. S., and B. A. GILCHREST. 1990. “The Senile Epidermis: Environmental Influences on Skin Ageing and Cutaneous Carcinogenesis”. British Journal of Dermatology. Wiley. doi:10.1111/j.1365-2133.1990.tb16126.x.

Microvascular ResearchJournal

The Effect of Aging on the Cutaneous Microvasculature

Bentov, Itay, and May J. Reed. 2015. “The Effect of Aging on the Cutaneous Microvasculature”. Microvascular Research. Elsevier BV. doi:10.1016/j.mvr.2015.04.004.

British Journal of DermatologyJournal

Is Skin Ageing in the Elderly Caused by Sun Exposure or Smoking?

Leung, W-C., and I. Harvey. 2002. “Is Skin Ageing in the Elderly Caused by Sun Exposure or Smoking?”. British Journal of Dermatology. Wiley. doi:10.1046/j.1365-2133.2002.04991.x.

Dermatology and TherapyJournal