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Improved PET Imaging Techniques for Scans

Phase 4
Waitlist Available
Led By Bradley Kemp, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

This trial will assess a new software's effectiveness on a new PET/CT scanner. They will also evaluate how well the scanner collects and processes data.

Who is the study for?
This trial is for adults who can understand and follow instructions, have had a positive PET/CT scan recently (for certain participants), and women must not be pregnant. It's not suitable for those unable to remain still for the required time during scans or who cannot prepare as instructed.Check my eligibility
What is being tested?
The study tests new software on a PET/CT scanner, focusing on improving image quality using motion correction, parametric imaging, and advanced reconstruction techniques. Participants will undergo scans with this technology to evaluate its effectiveness.See study design
What are the potential side effects?
There are no direct side effects mentioned from the interventions being tested since they involve non-invasive imaging techniques. However, standard risks associated with PET/CT scans may apply.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Map Reconstruction
Motion Correction
Parametric Imaging

Trial Design

2Treatment groups
Active Control
Group I: Parametric ImagingActive Control2 Interventions
Aim 2 involves the prospective data collection of subjects undergoing brain or whole body oncologic PET/CT scans on the V600-R1. The purpose of this arm is to evaluate the data acquisition and image processing workflow.
Group II: Motion CorrectionActive Control1 Intervention
Aim 1 involves the prospective data collection of subjects who are already enrolled in Mayo Clinic Rochester research study 08-005553 (PI: Dr Val Lowe) and are scheduled to be scanned on the Siemens Biograph Vision 600 PET/CT system (hereafter referred to as the V600-R1) in the PET/CT Molecular Imaging Research Center on Charlton 6 of Mayo Clinic Rochester. The purpose of this arm is to evaluate the effectiveness of motion correction software.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,205 Previous Clinical Trials
3,766,714 Total Patients Enrolled
Bradley Kemp, PhDPrincipal InvestigatorMayo Clinic

Media Library

Parametric Imaging Clinical Trial Eligibility Overview. Trial Name: NCT04417998 — Phase 4
Whole Body Scan Research Study Groups: Parametric Imaging, Motion Correction
Whole Body Scan Clinical Trial 2023: Parametric Imaging Highlights & Side Effects. Trial Name: NCT04417998 — Phase 4
Parametric Imaging 2023 Treatment Timeline for Medical Study. Trial Name: NCT04417998 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In what situations is Motion Correction commonly prescribed?

"Motion Correction is commonly used to treat left ventricular dysfunction, as well as cognitive impairment (CI), seizures, epileptic episodes, and chronic traumatic encephalopathy (CTE)."

Answered by AI

How many participants are there in this research endeavor?

"Unfortunately, this trial is not currently accepting participants. Initially posted on June 3rd 2020 and last updated May 11th 2022, patients are encouraged to examine the other 20 trials actively enrolling individuals for Motion Correction or 4 studies searching for volunteers with whole body imaging."

Answered by AI

Are recruitment efforts underway for this research project?

"Recruitment for this trial has ceased. It was initially posted June 3rd 2020, and the most recent update occurred on May 11th 2022. For those seeking alternative trials, currently 4 have begun recruitment involving whole body imaging and 20 studies related to Motion Correction are actively recruiting patients."

Answered by AI

Are there precedent studies related to Motion Correction?

"At present, 20 studies are in progress concerning Motion Correction. One of these is at Phase 3 and the other 19 trials are based around Wuhan, Hubei. Moreover, 21 locations worldwide have begun to research this potential treatment modality."

Answered by AI

What deleterious effects might individuals experience through the use of Motion Correction?

"Based on available clinical data, the safety of Motion Correction is estimated to be 3. This treatment has been approved by regulatory authorities and is in its fourth phase of trials."

Answered by AI

Who else is applying?

What state do they live in?
Wisconsin
How old are they?
18 - 65
What site did they apply to?
Mayo Clinic in Rochester
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction
Bradley Kemp 2020. "Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04417998.
~9 spots leftby Dec 2024
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