Simvastatin - Obese for Obesity

"This investigation is no longer seeking new patients. It was posted on June 1st 2019 and last updated February 3rd 2022. Those hoping to participate in similar studies may wish to investigate the 1020 obesity-related trials or 141 Roux-en-Y gastric bypass bariatric surgery investigations which are currently recruiting volunteers."

"This medical trial has concluded recruiting and is no longer actively seeking participants. Initially posted on June 1st 2019, it was most recently edited on February 3rd 2022. For those looking for alternative studies, there are 1020 trials presently requiring people with obesity and 141 demanding volunteers to undergo Roux-en-Y gastric bypass bariatric surgery."

"We assign a score of 3 to Roux-en-Y gastric bypass bariatric surgery due to the medical evidence that supports its approval."

"Candidates accepted into this study must have a diagnosis of obesity and should be within the 18 to 65 year old range. The recruitment phase aims for 120 participants in total."

"This clinical trial mandates patients to be aged 18-65. There are 233 trials available for participants younger than the age of consent, and 755 studies open to those who surpass 65 years old."

"The primary outcome of this carvedilol study is to conduct pharmacokinetic analysis on simvastatin over a 24 hour period. Secondary objectives include genotyping the essential SNPs found in CYP2C9, CYP2D6, ABCB1 and SLCO1B1 genes via RT-PCR, phenotyping for CYP3A4 utilising midazolam as a probe drug (determined through chromatographic analysis), and evaluating the CYP2D6 phenotype using metoprolol as an indicator substance (assessed by measuring urinary concentration ratio)."

"Since 2005, Merck Sharp & Dohme LLC has been researching Roux-en-Y gastric bypass bariatric surgery and completed their first trial in the same year. This initial research involving 80 people led to its Phase 4 drug approval; presently, 141 active studies are being conducted across 798 cities and 44 countries."

"Roux-en-Y gastric bypass bariatric surgery is the preferred preoperative sedation technique, but it can be equally effective for hypertensive disease, seizures, epileptic disorders and memory loss."

"Currently, there are 141 live clinical trials for Roux-en-Y gastric bypass bariatric surgery with 26 of them in the advanced Phase 3. Although a number of these experiments have been founded in Porto Alegre, California, 2187 institutions worldwide are hosting studies related to this process."