MoviPrep for Bowel Prep for Colonoscopy

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Bowel Prep for ColonoscopyMoviPrep - Drug
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether a low-volume bowel preparation is as effective as a standard high-volume preparation for hospitalized patients undergoing colonoscopy.

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

1 Primary · 9 Secondary · Reporting Duration: At time of procedure, approximately 45 minutes

Day 5
Hospital Length of Stay
At time of procedure, approximately 45 minutes
BBPS Score During Colonoscopy Withdrawal For Each Segment
Boston Bowel Preparation Score (BBPS) During Colonoscopy Withdrawal
Cecal Intubation Rate
Cecal Intubation Time
Colonoscopy Withdrawal Time
Intestines
Time to Endoscopy
Immediately prior to procedure
Intestines
Day 3
Number of Participants with Treatment-Related Adverse Events as Assessed by CTCAE v5.0

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Side Effects for

MiraLAX 306 g (Day-Prior)
60%Bloating
33%Nausea
33%Abdominal Cramps/Pain
9%Vomiting
This histogram enumerates side effects from a completed 2014 Phase 4 trial (NCT01719653) in the MiraLAX 306 g (Day-Prior) ARM group. Side effects include: Bloating with 60%, Nausea with 33%, Abdominal Cramps/Pain with 33%, Vomiting with 9%.

Trial Design

2 Treatment Groups

GoLYTELY
1 of 2
MoviPrep
1 of 2

Active Control

Experimental Treatment

450 Total Participants · 2 Treatment Groups

Primary Treatment: MoviPrep · No Placebo Group · Phase 4

MoviPrep
Drug
Experimental Group · 1 Intervention: MoviPrep · Intervention Types: Drug
GoLYTELY
Drug
ActiveComparator Group · 1 Intervention: Golytely · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Sodium chloride
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: at time of procedure, approximately 45 minutes

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,678 Previous Clinical Trials
21,087,363 Total Patients Enrolled
Darrick K Li, MD, PhDPrincipal InvestigatorYale School of Medicine

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are able to take bowel preparation and be willing to adhere to the regimen.
You must be aged 18 or greater.
You are scheduled to undergo colonoscopy.
References