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Prostaglandin E1 Analog

Vaginal Misoprostol for Induction of Labour

N/A

Waitlist Available

Led By Emily H Adhikari, MD

Research Sponsored by University of Texas Southwestern Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from start of induction agent to time of delivery

Awards & highlights

Study Summary

This trial will compare vaginal and oral misoprostol to see which is more effective in inducing labor in a high-volume setting.

Eligible Conditions

Induction of Labour
Pregnancy

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at delivery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at delivery

This trial's timeline: 3 weeks for screening, Varies for treatment, and at delivery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants with Vaginal Delivery

Secondary outcome measures

Indication for Cesarean Delivery

Need for Oxytocin

Number of Participants That Needed Mechanical Ventilation in Delivery Room (Yes/No)

+16 more

Side effects data

From 2017 Phase 4 trial • 70 Patients • NCT03134183

Expulsion

100%

80%

60%

40%

20%

Study treatment Arm

Vaginal Misoprostol

Buccal Misoprostol

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Vaginal MisoprostolExperimental Treatment1 Intervention

Patients will receive vaginal misoprostol 25 micrograms given every 3 hours for a maximum of 5 doses

Group II: Oral MisoprostolActive Control1 Intervention

Patients will receive oral misoprostol 100 micrograms given every 4 hours for a maximum of 2 doses.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor

1,047 Previous Clinical Trials

1,051,253 Total Patients Enrolled

1 Trials studying Induction of Labour

2,227 Patients Enrolled for Induction of Labour

Emily H Adhikari, MDPrincipal InvestigatorUniversity of Texas Southwestern Medical Center

1 Previous Clinical Trials

2,227 Total Patients Enrolled

1 Trials studying Induction of Labour

2,227 Patients Enrolled for Induction of Labour

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the projected enrollment size for this experiment?

"Affirmative. According to the records on clinicaltrials.gov, this medical trial which was first advertised on May 24th 2021 is still recruiting participants. The study requires 2154 individuals from 1 hospitals/clinics."

Answered by AI

Are there still vacancies for enrollees in this research project?

"Affirmative. Information posted on clinicaltrials.gov illustrates that this medical trial is presently in search of volunteers; the study was first made available on May 24th 2021 and its most recent edit came on September 27th 2022. 2154 participants are sought from 1 distinct site for enrolment into the experiment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Labor Induction With Oral Versus Vaginal Misoprostol

Emily Adhikari 2021. "Labor Induction With Oral Versus Vaginal Misoprostol". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04755218.