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True Cognitive Training Nocebo for Cognitive Impairment
N/A
Waitlist Available
Led By Aaron Seitz, PhD
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post-test 1 at 25 days, post-test 2 at 34 days
Awards & highlights
Study Summary
This trial is designed to study whether people's expectations about a cognitive training task can affect their performance on the task, as well as whether the placebo effect can be harnessed to improve performance.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ post-test 1 at 25 days, post-test 2 at 34 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post-test 1 at 25 days, post-test 2 at 34 days
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Difference in Response Time Between Switch Trials and Non-switch Trials (Switch Cost) in the Countermanding Task
Difference in Response Time Between Switch Trials and Non-switch Trials (Switch Cost) in the Task Switching Task
Difference in Response Time of Compatible Trials and Incompatible Trials in the Attentional Network Task (ANT)
+9 moreTrial Design
4Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: True Cognitive Training PlaceboExperimental Treatment2 Interventions
Participants will receive a positive expectation message (e.g., "Previous research has shown that training with this program improves performance on other tasks.") and will complete approximately 7 hours of a cognitive training program that has previously been shown to improve cognition.
Group II: True Cognitive Training NoceboActive Control2 Interventions
Participants will receive a negative expectation message (e.g., "Previous research has shown that training with this program decreases performance on other tasks.") and will complete approximately 7 hours of a cognitive training program that has previously been shown to improve cognition.
Group III: Control Cognitive Training NoceboPlacebo Group2 Interventions
Participants will receive a negative expectation message (e.g., "Previous research has shown that training with this program decreases performance on other tasks.") and will complete approximately 7 hours of control training program that has not previously been shown to improve cognition.
Group IV: Control Cognitive Training PlaceboPlacebo Group2 Interventions
Participants will receive a positive expectation message (e.g., "Previous research has shown that training with this program increases performance on other tasks.") and will complete approximately 7 hours of control training program that has not previously been shown to improve cognition.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
True Cognitive Training Program
2020
N/A
~290
Positive Expectation Induction
2020
N/A
~290
Find a Location
Who is running the clinical trial?
University of California, IrvineOTHER
544 Previous Clinical Trials
1,922,756 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,672 Previous Clinical Trials
28,018,376 Total Patients Enrolled
University of Wisconsin, MadisonLead Sponsor
1,186 Previous Clinical Trials
3,169,160 Total Patients Enrolled
Frequently Asked Questions
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