This trial is evaluating whether Outdoor Exercise will improve 1 primary outcome and 4 secondary outcomes in patients with Hematoietic Cell Transplant. Measurement will happen over the course of 1 week, 5 weeks.
This trial requires 20 total participants across 2 different treatment groups
This trial involves 2 different treatments. Outdoor Exercise is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Signs and symptoms vary and are not always present, and often reflect the severity of the disease or its prior therapy. Symptoms include abnormal skin pigmented lesions, itch, and fever." - Anonymous Online Contributor
"Hematopoietic cell transplant is a safe and effective treatment for hematologic diseases. The recipient's immune system works to eliminate the non-self cells in recipients' body. The non-self cells are T cells and natural killer cells. The transplant of bone marrow, stem cells, peripheral blood stem cells, or progenitor cells will regenerate these cells. It is most effective to use the hematopoietic stem cell transplant, not because of its function has no stem cells, but because the function of stem cells can not only rejuvenate blood cells and make them healthy, but also prolong the life of the recipients in order to avoid the complication of the transplant." - Anonymous Online Contributor
"Hematopoietic stem cell transplantation appears to be the cause of only a few of the chronic graft-versus-host disease cases, or a few of the autoimmune diseases. We postulate that all of the autoimmunity cases have an underlying condition that is not graft-versus-host-based." - Anonymous Online Contributor
"Although there is still a lack of well studied and verified strategies for cancer cure, a few things are achievable. These include the use of gene-modified T cells, autologous stem cell therapy, and adoptive cell transfer. These will be used sparingly to treat disease that has been present for long periods of time. The last approach is the most likely to be tested in a clinic. In most cases, these techniques should be used to treat advanced cancers. Current chemotherapy and/or some other type of cancer treatments should be used to treat the cancer before considering any of the new types of therapies." - Anonymous Online Contributor
"HemAT's are a common, critical part of HCT for hematological malignancies, with good long-term outcomes, low treatment-related mortality, and a low need for HSCT. It does have to be said that blood is a precious resource, and thus it is hard to justify the large amounts of money spent on the collection, testing, and treatment of blood donors." - Anonymous Online Contributor
"We calculated the overall number of patients, from their diagnosis of hematologic diseases, who would be eligible for HAET in the United States. There was high variability of eligibility for consideration for HAET in each country-more than any other factor. This information will help to better understand disparities in access to HAET among countries." - Anonymous Online Contributor
"To our knowledge, no large cohort has previously characterized this family. In a recent study, findings suggest that an HCT run in families may occur, but should be recognized as a rare event." - Anonymous Online Contributor
"There has been the introduction of a vast range of new outdoor activities that have been used as therapies. A wider acceptance is being given to the potential role that outdoor activities such as cycling, trekking, hiking, biking, canoeing and kayaking can play in the management of a significant number of health conditions, including cardiovascular diseases. It is imperative in these cases that they be conducted in an appropriate way to avoid negative consequences." - Anonymous Online Contributor
"Recent findings of this study suggest that there was no advantage of a 12-mile walk over a placebo. Outdoor walking may be effective for reducing distress of pediatric patients. Outdoor exercise may be beneficial to children who are unwell, with a poor appetite, or with anemia, while a multidisciplinary approach to management may be more effective than a particular type of activity, but this needs to be confirmed. Other forms of exercise may be an effective treatment, such a swimming and a ball game. However, further research, maybe by a larger amount of patients, is necessary to prove the potential benefits of outdoor exercise for a wide range of pediatric patients' conditions." - Anonymous Online Contributor
"Moderate to high intensity outdoor exercise training increases exercise capacity, as measured by CPET, and increases peripheral insulin sensitivity and the hypothalamic/pituitary-adrenocortical axis (HPA) reactivity, independently of age, gender, and fitness level." - Anonymous Online Contributor
"There does not appear to be a safety concern associated with outdoor activity. More recent studies have also found that there is no increased risk of malignancy associated with outdoor physical activity. However, people with pre-existing medical conditions can benefit from outdoor health-supportive activity. Therefore, it is imperative that all people are urged to partake regularly in physical activity and to enjoy the outdoors regardless of their pre-existing health conditions." - Anonymous Online Contributor
"Outdoor exercise is used with many other treatments including chemotherapy, radiation, and corticosteroids. Outdoor exercise should be considered as one of the therapies when cancer is treated." - Anonymous Online Contributor