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TAP and Rectus Sheath ropivacaine for Bariatric Surgery Candidates (LapTAP Trial)

Phase 4
Waitlist Available
Led By Joseph Mamazza, MD
Research Sponsored by Ottawa Hospital Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0-24 hour post operatively
Awards & highlights

LapTAP Trial Summary

Randomized, Double-Blinded, Placebo-Controlled Trial of Laparoscopic Transverse Abdominis Plane (Lap TAP) and Rectus Sheath Block in elective Gastric Bypass Surgery aiming to evaluate the benefit of a laparoscopically -guided, surgical transversus abdominis plane (TAP) block and rectus sheath block in reducing post-operative opioid consumption and improving outcomes in patients undergoing laparoscopic gastric bypass surgery. The results of this study will provide further evidence on the optimal means to obtain analgesia in patients undergoing gastric bypass surgery

LapTAP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~hour 0-24 post operatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and hour 0-24 post operatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cumulative postoperative narcotic use
Secondary outcome measures
6-minute walk distance (6MWD)
Peak Expiratory flow score
Post-operative pain score
+1 more

LapTAP Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: TAP and Rectus Sheath ropivacaineExperimental Treatment1 Intervention
The block will be administered in the anterior abdominal wall. For the TAP block, the standard technique will be followed- at the anterior axillary line midway between the subcostal margin and iliac crest. For the rectus sheath block, a bilateral sub-xiphoid approach will be used. There will be 4 injection sites in total and the size of the needle will be standardized to an 18g spinal needle 10cms. Using laparoscopic visualization, the transversus abdominis muscles were identified lateral to the semilunar line. Ropivacaine to be infiltrated will be divided into 4 equal amounts. The procedure is then repeated 2 times in the transversus abdominis plane (20mL each) and 2 times as a Rectus Sheath Block (10mL each) with a total amount of 60 mL.
Group II: TAP and Rectus Sheath Normal SalinePlacebo Group1 Intervention
TAP and Rectus Sheath Block of 60 mL Normal Saline divided into 4 injections administered as in Experimental Arm.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ropivacaine
FDA approved

Find a Location

Who is running the clinical trial?

Ottawa Hospital Research InstituteLead Sponsor
561 Previous Clinical Trials
2,785,541 Total Patients Enrolled
1 Trials studying Bariatric Surgery Candidates
120 Patients Enrolled for Bariatric Surgery Candidates
Joseph Mamazza, MDPrincipal InvestigatorThe Ottawa Hospital
1 Previous Clinical Trials
120 Total Patients Enrolled
1 Trials studying Bariatric Surgery Candidates
120 Patients Enrolled for Bariatric Surgery Candidates

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)
2018. "The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03367728.
All > Gastric Bypass
~24 spots leftby Apr 2025
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