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Cholinesterase Inhibitor

Donepezil for Wound Healing

Phase 2
Recruiting
Research Sponsored by University of Maryland, Baltimore
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2-4 weeks
Awards & highlights

Study Summary

This trial will test if donepezil can help heal wounds in diabetes patients who haven't healed with standard treatment.

Eligible Conditions
  • Wound Healing

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2-4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2-4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in depth wound
Change in diameter of the wound

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Donepezil and Topical Zinc OxideExperimental Treatment2 Interventions
donepezil 5mg daily and topical zinc oxide 20% three times daily
Group II: Placebo and Topical Zinc OxidePlacebo Group2 Interventions
Placebo daily and topical zinc oxide 20% three times daily
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Donepezil
FDA approved

Find a Location

Who is running the clinical trial?

University of Maryland, BaltimoreLead Sponsor
687 Previous Clinical Trials
374,626 Total Patients Enrolled
1 Trials studying Wound Healing

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In what medical cases is Topical Zinc Oxide typically recommended?

"Topical Zinc Oxide can diminish discomfort and is a viable option for those with Alzheimer's disease, acute wounds, or sensitive skin."

Answered by AI

To what extent is the enrollment being maximized in this investigation?

"Affirmative. Clinicaltrials.gov records indicate that this research endeavour, which was initially posted on August 30th 2020, is presently recruiting subjects. Around 20 volunteers need to be gathered from a single medical facility."

Answered by AI

Is this a pioneering clinical trial?

"At present, 16 trials involving Topical Zinc Oxide are active across 19 cities and 7 nations. This pharmaceutical journey began in 2013 when Dong-A Pharmaceutical Co., Ltd sponsored an initial Phase 3 trial with a sample size of 210 patients. Subsequently, 242 studies have been concluded since then."

Answered by AI

What potentially hazardous effects may arise from topical zinc oxide application?

"Assessing the safety of topical zinc oxide, our team allocated a score of 2 as this Phase-2 trial has some data validating its safety profile but not efficacy."

Answered by AI

Are there any previous reports detailing the use of Topical Zinc Oxide?

"Presently, 16 clinical trials are being conducted to examine the efficacy of Topical Zinc Oxide. Out of these studies, two have advanced to Phase 3. Hallandale Beach in Florida serves as a hub for research on this medication, however 29 other medical centres across the country are also involved with its trial period."

Answered by AI

Does this experiment need more volunteer participation?

"Affirmative, the data hosted on clinicaltrials.gov display that this medicinal experiment is currently recruiting participants. This study was initially made available to the public on August 30th 2020 and has since been updated October 20th 2021. The trial requires roughly 20 patients at a single location."

Answered by AI
~4 spots leftby Apr 2025