Donepezil for Wound Healing

Phase-Based Progress Estimates
University of Maryland Shore Medical Center at Easton, Easton, MDWound HealingDonepezil - Drug
All Sexes
What conditions do you have?

Study Summary

This trial will test if donepezil can help heal wounds in diabetes patients who haven't healed with standard treatment.

Eligible Conditions
  • Wound Healing

Treatment Effectiveness

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 2-4 weeks

2-4 weeks
Change in depth wound
Change in diameter of the wound

Trial Safety

Trial Design

2 Treatment Groups

Donepezil and Topical Zinc Oxide
1 of 2
Placebo and Topical Zinc Oxide
1 of 2

Experimental Treatment

Non-Treatment Group

20 Total Participants · 2 Treatment Groups

Primary Treatment: Donepezil · Has Placebo Group · Phase 2

Donepezil and Topical Zinc OxideExperimental Group · 2 Interventions: Donepezil, Topical Zinc Oxide · Intervention Types: Drug, Drug
Placebo and Topical Zinc OxidePlaceboComparator Group · 2 Interventions: Topical Zinc Oxide, Placebo oral tablet · Intervention Types: Drug, Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2-4 weeks

Who is running the clinical trial?

University of Maryland, BaltimoreLead Sponsor
617 Previous Clinical Trials
355,978 Total Patients Enrolled
1 Trials studying Wound Healing

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

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Frequently Asked Questions

In what medical cases is Topical Zinc Oxide typically recommended?

"Topical Zinc Oxide can diminish discomfort and is a viable option for those with Alzheimer's Disease, acute wounds, or sensitive skin." - Anonymous Online Contributor

Unverified Answer

To what extent is the enrollment being maximized in this investigation?

"Affirmative. records indicate that this research endeavour, which was initially posted on August 30th 2020, is presently recruiting subjects. Around 20 volunteers need to be gathered from a single medical facility." - Anonymous Online Contributor

Unverified Answer

Is this a pioneering clinical trial?

"At present, 16 trials involving Topical Zinc Oxide are active across 19 cities and 7 nations. This pharmaceutical journey began in 2013 when Dong-A Pharmaceutical Co., Ltd sponsored an initial Phase 3 trial with a sample size of 210 patients. Subsequently, 242 studies have been concluded since then." - Anonymous Online Contributor

Unverified Answer

What potentially hazardous effects may arise from topical zinc oxide application?

"Assessing the safety of topical zinc oxide, our team allocated a score of 2 as this Phase-2 trial has some data validating its safety profile but not efficacy." - Anonymous Online Contributor

Unverified Answer

Are there any previous reports detailing the use of Topical Zinc Oxide?

"Presently, 16 clinical trials are being conducted to examine the efficacy of Topical Zinc Oxide. Out of these studies, two have advanced to Phase 3. Hallandale Beach in Florida serves as a hub for research on this medication, however 29 other medical centres across the country are also involved with its trial period." - Anonymous Online Contributor

Unverified Answer

Does this experiment need more volunteer participation?

"Affirmative, the data hosted on display that this medicinal experiment is currently recruiting participants. This study was initially made available to the public on August 30th 2020 and has since been updated October 20th 2021. The trial requires roughly 20 patients at a single location." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.