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Guanfacine for Substance Use Disorder
Study Summary
This trial will test if guanfacine can help reduce drug craving and improve cognitive flexibility in women with substance use disorder in an outpatient setting.
- Substance Use Disorder
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2011 Phase 4 trial • 212 Patients • NCT00429273Trial Design
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- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Frequently Asked Questions
Has Guanfacine been given a green light by the FDA?
"While there is some clinical evidence of the safety profile for Guanfacine, efficacy has yet to be proven. As such, our team at Power assigned it a score of 2 on the risk scale from 1-3."
Does this research program accept elderly participants?
"This trial has outlined that applicants between 18 and 70 years of age are eligible to participate. There is a total of 77 trials for minors, while those above the retirement threshold have access to 260 different studies."
Has there been any prior research concerning the effects of Guanfacine?
"Currently, there are 9 trials exploring the effects of guanfacine with 2 in Phase 3. The overwhelming majority of these studies have been set up at locations across Palo Alto, California. In total, 80 clinical sites now offer this medication for study and research purposes."
Can you elucidate the primary conditions which can be alleviated by taking Guanfacine?
"Guanfacine is frequently dispensed to alleviate migraine symptoms. Other conditions that can be treated with guanfacine include attention deficit hyperactivity disorder (ADHD), hypertensive disease, and prevention of migraines."
Is enrollment for this research still open?
"Verified. According to the information found on clinicaltrials.gov, this medical trial is in search of participants and was first made available for recruitment on November 1st 2019. Recent updates were applied on July 22nd 2022 and it aims to enrol 14 patients from a single site."
How many participants are actively involved in this investigation?
"Affirmative. Clinicaltrials.gov shows that this clinical study, which first went live on the 1st of November 2019, is now actively recruiting participants. A total of 14 people needs to be sourced from a single medical centre for the trial to move forward."
What criteria must be met in order for a person to qualify for this medical experiment?
"This medical trial requires 14 individuals, ranging in age from 18 to 70 years old who have a drug addiction. Patients must additionally fulfil the following requirements: 100 treatment-seeking females, informed verbal and written consent indicating they meet DSM-V criteria for concurrent Substance Use Disorders (SUDs) with either primary cocaine or opioid use disorder plus co-occurring cannabis, alcohol or nicotine abuse; BMI between 18 and 35."
Is this medical experiment the inaugural effort of its kind?
"Presently, there are 9 ongoing studies on guanfacine that span multiple cities and countries. Shire initially sponsored a trial of 20 participants in 2018 which has since been concluded. Since then, 52 experiments have successfully finished."
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