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Brief Enhanaced Exposure Therapy for Post-Traumatic Stress Disorder

Phase 2
Waitlist Available
Led By Michael J Telch, Ph.D.
Research Sponsored by University of Texas at Austin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 6, 10, 22
Awards & highlights

Study Summary

This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others. The goal of the study is to determine whether this experimental treatment outperforms the well-established standard treatment.

Eligible Conditions
  • Post-Traumatic Stress Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 6, 10, 22
This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 6, 10, 22 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from baseline in PTSD symptom severity
Secondary outcome measures
Change from baseline in depression symptom severity
Change from baseline in general physical and psychological health
Change from baseline in trauma-related cognitions
+1 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Brief Enhanaced Exposure TherapyExperimental Treatment7 Interventions
The following interventions are included in this arm: Psycho-education addressing common reactions to trauma Revisiting the Trauma memories Processing the trauma memories In vivo Exposure homework *Use of a brief pre-exposure trauma memory retrieval trial Exposure to video clips related to the patient's trauma Compound extinction - simultaneously exposing patient to trauma video clips while they listen to their trauma script
Group II: Standard Prolonged Exposure TherapyActive Control5 Interventions
The following interventions are included in this arm: Psycho-education addressing common reactions to trauma Revisiting of the Trauma memories Processing the trauma memories Breathing retraining In vivo Exposure homework
Group III: Delayed Treatment ControlActive Control1 Intervention
Patients assigned to this arm receive assessment only (Week 0, 3, and 6) prior to receiving standard prolonged exposure therapy using the Foa et al treatment manual.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Psychoeducation
2005
Completed Phase 2
~3310

Find a Location

Who is running the clinical trial?

University of PennsylvaniaOTHER
1,999 Previous Clinical Trials
42,879,415 Total Patients Enrolled
University of Texas at AustinLead Sponsor
349 Previous Clinical Trials
80,357 Total Patients Enrolled
Michael J Telch, Ph.D.Principal InvestigatorUniversity of Texas at Austin
4 Previous Clinical Trials
424 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Texas
How old are they?
18 - 65
What site did they apply to?
Laboratory for the Study of Anxiety Disorders, University of Texas at Austin
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
Michael J. Telch 2012. "Enhancing Exposure Therapy for Post-traumatic Stress Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01574118.
~2 spots leftby Apr 2025
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