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Anti-metabolites

POLF regimen for Gastric Cancer

Phase 2
Waitlist Available
Led By Jie Liu, M.D.
Research Sponsored by Huashan Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
pathologically confirmed gastric cancer AJCC stage III or IV
measurable disease based on CT or endoscopy exam
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

phase II study of weekly metronomic chemotherapy using weekly Paclitaxel, Oxaliplatin, Leucovorin and 5-FU (POLF) in patients with advanced gastric cancer

Eligible Conditions
  • Gastric Cancer

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
response rate
Secondary outcome measures
adverse events
overall survival
progression free survival

Trial Design

1Treatment groups
Experimental Treatment
Group I: POLF regimenExperimental Treatment1 Intervention
Paclitaxel 60mg/m2, Oxaliplatin 50mg/m2, Leucovorin 20mg/m2, and 5-FU 425mg/m2 IV weekly

Find a Location

Who is running the clinical trial?

Huashan HospitalLead Sponsor
302 Previous Clinical Trials
14,685,337 Total Patients Enrolled
Seattle Integrative Cancer CenterUNKNOWN
Jie Liu, M.D.Principal InvestigatorHuashan Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Metronomic Chemotherapy in Advanced Gastric Cancer
Nick Chen 2015. "Metronomic Chemotherapy in Advanced Gastric Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02855788.
All > Debbies Dream > Gastric Cancer
~4 spots leftby Apr 2025
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