← Back to Search

Nonsteroidal Anti-inflammatory Drug

Drug order 2 for Ankylosing Spondylitis

Phase 2
Waitlist Available
Led By Mark C Hwang, MD
Research Sponsored by The University of Texas Health Science Center, Houston
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up visit 7,week 29
Awards & highlights

Study Summary

This trial is testing if COX-2 and non-selective COX inhibitors improve disease activity and health-related quality of life for those with axial spondyloarthritis, as well as assessing if there are predictive biomarkers of NSAID response.

Eligible Conditions
  • Ankylosing Spondylitis
  • Epidural Block

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~visit 7,week 29
This trial's timeline: 3 weeks for screening, Varies for treatment, and visit 7,week 29 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Extent of disease activity as measured by the Ankylosing Spondylitis Disease Activity Score (ASDAS)
Secondary outcome measures
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Bath Ankylosing Spondylitis Metrology Index (BASMI)
Change in ability to perform tasks as assessed by the Bath Ankylosing Spondylitis Functional Index (BASFI)
+4 more

Trial Design

6Treatment groups
Experimental Treatment
Group I: Drug order 6Experimental Treatment1 Intervention
Group II: Drug order 5Experimental Treatment1 Intervention
Group III: Drug order 4Experimental Treatment1 Intervention
Group IV: Drug order 3Experimental Treatment1 Intervention
Group V: Drug order 2Experimental Treatment1 Intervention
Group VI: Drug order 1Experimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Drug order 1
2020
Completed Phase 2
~50
Drug order 5
2020
Completed Phase 2
~50
Drug order 6
2020
Completed Phase 2
~50
Drug order 2
2020
Completed Phase 2
~50
Drug order 4
2020
Completed Phase 2
~50
Drug order 3
2020
Completed Phase 2
~50

Find a Location

Who is running the clinical trial?

National Center for Advancing Translational Science (NCATS)NIH
99 Previous Clinical Trials
36,267 Total Patients Enrolled
National Center for Advancing Translational Sciences (NCATS)NIH
320 Previous Clinical Trials
401,688 Total Patients Enrolled
The University of Texas Health Science Center, HoustonLead Sponsor
903 Previous Clinical Trials
320,935 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the safety implications of administering Drug order 2?

"Drug order 2 was assessed with a score of two, as it is in the Phase 2 trial phase and has only been tested for safety; there isn't any evidence to back its effectiveness thus far."

Answered by AI

How many individuals are actively engaged in this research endeavor?

"Affirmative, clinicaltrials.gov data confirms that this medical project is recruiting participants. It was published on the 25th of June 2020 and recently edited on 28th February 2022. This study requires 75 patients for one particular site."

Answered by AI

Are there any opportunities left to join this research endeavor?

"According to the clinicaltrials.gov page, this experiment is actively seeking subjects; it was opened up on June 25th 2020 and last revised February 28th 2022."

Answered by AI

Who else is applying?

What state do they live in?
Texas
How old are they?
18 - 65
What site did they apply to?
The University of Texas Health Science Center at Houston
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
Recent research and studies
clinicaltrials.govStudy
Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials
Mark C Hwang 2020. "Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04115098.
~9 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top