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Monoclonal Antibodies

Ublituximab for Multiple Sclerosis

Phase 2
Waitlist Available
Research Sponsored by TG Therapeutics, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 96 weeks
Awards & highlights

Study Summary

This trial looks at the effects of using ublituximab, a new monoclonal antibody, to treat patients with relapsing multiple sclerosis.

Eligible Conditions
  • Multiple Sclerosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 96 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 96 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of participants with treatment-related events as assessed by CTCAE V4.0
Secondary outcome measures
Evaluate the % of participants with relapses

Trial Design

1Treatment groups
Experimental Treatment
Group I: UblituximabExperimental Treatment1 Intervention
Ublituximab IV infusions on Weeks 1E, 24E, 48E, 72E and (6E
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ublituximab
2017
Completed Phase 3
~2040

Find a Location

Who is running the clinical trial?

TG Therapeutics, Inc.Lead Sponsor
36 Previous Clinical Trials
5,583 Total Patients Enrolled
6 Trials studying Multiple Sclerosis
2,559 Patients Enrolled for Multiple Sclerosis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential adverse effects could be associated with Ublituximab?

"As a Phase 2 trial, Ublituximab is believed to have some safety data but has yet to be proven effective in clinical trials. Therefore, it received an assessment of 2 on our scale."

Answered by AI

Are there still openings for participants in this clinical experiment?

"Data on clinicaltrials.gov affirms that, since its inception in June 2017 and last update November 2021, this medical trial is not actively recruiting patients. However, there are 560 other trials which are currently accepting participants for their study."

Answered by AI

What earlier experiments have been conducted with Ublituximab?

"In 2015, the initial ublituximab trials took place at TG Therapeutics Investigational Trial Site. Currently there have been 9 finished studies and 11 ongoing ones; many of which are being administered in Pasadena, California."

Answered by AI

Are the elderly being included in this research endeavor?

"To qualify for this medical trial, prospective participants must be aged 18 or higher and no older than 55."

Answered by AI

Who meets the criteria to partake in this research trial?

"To qualify for this medical trial, potential participants must have been diagnosed with multiple sclerosis and be in the age range of 18 to 55. Currently, 48 people are being sought after as study enrollees."

Answered by AI

How many health centers have been enlisted to participate in this research endeavor?

"This investigation is taking place in 8 distinct medical centres, including Pasadena, Lexington and San Antonio. It may be prudent to choose the closest site available when enrolling so as to reduce travel needs."

Answered by AI

Does this medical research represent a pioneering effort?

"Since its initial trial in 2015, sponsored by TG Therapeutics Inc., Ublituximab has been successful and achieved Phase 3 drug approval. Nowadays, 11 active clinical trials for the medication are ongoing within 133 cities across 13 countries."

Answered by AI

What is the sample size for this clinical investigation?

"This clinical trial has closed for recruitment. It had been posted on June 1st 2017 and the latest update was November 21st 2022. If you are in search of alternative trials, there are presently 549 recruiting studies investigating multiple sclerosis and 11 accepting patients that require Ublituximab treatment."

Answered by AI
~6 spots leftby Apr 2025