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Proton Beam Therapy

surgery (wide local excision; limb preservation surgery) for Soft Tissue Sarcoma

N/A

Waitlist Available

Led By Gary Yang, MD

Research Sponsored by Loma Linda University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at 2 years from the start of radiation treatment

Awards & highlights

Study Summary

This trial will compare side effects and tumor recurrence in patients who have proton radiation with those who have traditional radiation therapy.

Eligible Conditions

Soft Tissue Sarcoma

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and at 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Late Radiation Toxicities at 2 Years From the Start of Radiation Treatment

Secondary outcome measures

Grade 3-5 Adverse Events at 6 Months From the Start of Radiation Treatment.

Patterns of Failure at 6 Months

Patterns of Failure at 6 Months From the Start of Radiation Treatment

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Preoperative proton radiationExperimental Treatment2 Interventions

Patients will receive 50 Gray equivalents (GyE) in 25 fractions with proton therapy, followed by surgery 4-8 weeks after completion of radiation.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

surgery (wide local excision; limb preservation surgery)

2013

N/A

~10

proton radiation

2013

N/A

~10

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Loma Linda UniversityLead Sponsor

306 Previous Clinical Trials

260,977 Total Patients Enrolled

Gary Yang, MDPrincipal Investigator - gyang@llu.edu

Loma Linda University

3 Previous Clinical Trials

82 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any remaining opportunities for people to participate in this experiment?

"According to the clinicaltrials.gov entry, this trial is actively seeking recruits and has been since its initial posting on February 27th 2013. The listing was most recently modified on February 16th 2022."

Answered by AI

Does this clinical research include participants of mature age?

"This clinical trial has defined an age range of 18 to 98 years old. Additionally, it is offering 156 trials for participants under the age of consent and 365 trials are available for people over 65."

Answered by AI

How many participants are being admitted to this trial?

"Affirmative, clinicaltrials.gov records indicate that this research is actively looking to recruit participants. It was first published on February 27th 2013 and recently updated on February 16th 2022. 51 volunteers are needed from a single testing site."

Answered by AI

May I participate in this investigation?

"In order to qualify for inclusion in this research, candidates must be suffering from soft tissue sarcoma (STS) and fall within the ages of 18-98. Presently, approximately 51 participants are being sought after."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall

Gary Yang, MD 2013. "A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01819831.