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Monoclonal Antibodies

Risankizumab for Psoriasis (LIMMITLESS Trial)

Phase 3
Waitlist Available
Research Sponsored by AbbVie
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from first dose of study drug until 20 weeks after last dose of study drug (up to 272 weeks)
Awards & highlights

LIMMITLESS Trial Summary

This trial will test the safety and effectiveness of a new psoriasis drug over a long period of time.

LIMMITLESS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from first dose of study drug until 20 weeks after last dose of study drug (up to 272 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and from first dose of study drug until 20 weeks after last dose of study drug (up to 272 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants With Adverse Events
Secondary outcome measures
Percentage of Participants Achieving At Least 100% Reduction in PASI Score From Baseline (PASI 100)
Percentage of Participants Achieving At Least 75% Reduction in PASI Score From Baseline (PASI 75)
Percentage of Participants Achieving At Least 90% Reduction in Psoriasis Area and Severity Index (PASI) Score From Baseline (PASI 90)
+2 more

Side effects data

From 2020 Phase 3 trial • 18 Patients • NCT03022045
25%
Urticaria
25%
Osteoarthritis
25%
Rash
25%
Intervertebral disc protrusion
25%
Hepatic function abnormal
25%
Alanine aminotransferase increased
25%
Aspartate aminotransferase increased
25%
Erythema
25%
Viral upper respiratory tract infection
25%
Gamma-glutamyltransferase increased
100%
80%
60%
40%
20%
0%
Study treatment Arm
GPP Risankizumab 75 mg
GPP Risankizumab 150 mg
EP Risankizumab 75 mg
EP Risankizumab 150 mg

LIMMITLESS Trial Design

1Treatment groups
Experimental Treatment
Group I: RisankizumabExperimental Treatment1 Intervention
Participants will receive risankizumab administered by subcutaneous injection.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
risankizumab
2016
Completed Phase 3
~5550

Find a Location

Who is running the clinical trial?

AbbVieLead Sponsor
954 Previous Clinical Trials
498,933 Total Patients Enrolled
62 Trials studying Psoriasis
123,440 Patients Enrolled for Psoriasis
AbbVie Inc.Study DirectorAbbVie
264 Previous Clinical Trials
99,385 Total Patients Enrolled
18 Trials studying Psoriasis
14,329 Patients Enrolled for Psoriasis
ABBVIE INC.Study DirectorAbbVie
394 Previous Clinical Trials
143,767 Total Patients Enrolled
22 Trials studying Psoriasis
15,891 Patients Enrolled for Psoriasis

Media Library

risankizumab (Monoclonal Antibodies) Clinical Trial Eligibility Overview. Trial Name: NCT03047395 — Phase 3
Psoriasis Research Study Groups: Risankizumab
Psoriasis Clinical Trial 2023: risankizumab Highlights & Side Effects. Trial Name: NCT03047395 — Phase 3
risankizumab (Monoclonal Antibodies) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03047395 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How does risankizumab compare to other drugs in its class?

"Risankizumab was first studied in 2011 at Memorial Sloan Kettering Cancer Center. As of now, there have been a total of 99 completed trials testing the efficacy of risankizumab. Additionally, 29 clinical trials are still ongoing; many of which are being conducted out of Verona, New jersey."

Answered by AI

Are participants still being enrolled in this experiment?

"This particular trial is no longer looking for new patients; however, if you are still interested in participating in a clinical study, there are currently 179 trials for psoriasis and 29 trials for risankizumab that are actively enrolling patients."

Answered by AI

Are there study sites in close proximity to each other?

"There are 100 sites running this trial, Verona, Santa Ana, Clinton Township and 97 other locations. Patients should try to select the location nearest to them in order to reduce travel time if they participate."

Answered by AI

How many patients are participating in this clinical trial?

"Unfortunately, this study is no longer recruiting patients. However, there are currently 179 other trials studying psoriasis and 29 trials investigating risankizumab that are still enrolling participants."

Answered by AI

When can patients in the USA expect to have access to risankizumab?

"Risankizumab's safety is estimated to be a 3. This conclusion is based on the fact that risankizumab is currently in Phase 3 trials, which suggests that while there is evidence of efficacy, further testing for safety is needed."

Answered by AI

Which medical condition is risankizumab primarily prescribed for?

"In addition to treating dental plaque, risankizumab can also be used for therapeutic interventions such as psoriasis management, skin disinfecting therapy, and alleviating symptoms associated with psoriatic arthritis."

Answered by AI

Who else is applying?

What state do they live in?
Kentucky
Texas
North Carolina
Other
How old are they?
18 - 65
What site did they apply to?
T. Joseph Raoof, MD, Inc. /ID# 154078
Skin Sciences, PLLC /ID# 153991
Dermatology Consulting Service /ID# 154010
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
1
Recent research and studies
~269 spots leftby Apr 2025