← Back to Search

Anti-tumor antibiotic

Antiandrogen Therapy for Prostate Cancer

Phase 2
Waitlist Available
Led By Jing Zeng
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 months
Awards & highlights

Study Summary

This trial is studying a combination of antiandrogen therapy, abiraterone acetate, and prednisone with or without neutron radiation therapy to treat prostate cancer.

Eligible Conditions
  • Hormone-Refractory Prostate Cancer
  • Prostate Adenocarcinoma
  • Prostate Carcinoma
  • Prostate Cancer
  • Bone Metastasis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent Change in Peripheral Blood Effector T-cells (CCR7-/CD45RO)
Secondary outcome measures
Incidence of Adverse Events
Rate of Undetectable Prostate Specific Antigen (PSA) (< 0.2)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Arm II (ADT, abiraterone, prednisone, radiation therapy)Experimental Treatment4 Interventions
Patients receive ADT, abiraterone acetate, and prednisone as in Arm I. Beginning 8-10 weeks after starting ADT and within 1 week of starting abiraterone acetate, patients also undergo 3-5 fractions of neutron radiation therapy for 2 weeks in the absence of disease progression or unacceptable toxicity.
Group II: Arm I (ADT, abiraterone, prednisone)Active Control3 Interventions
Patients receive ADT per standard of care. Beginning 2 months after start of ADT, patients also receive abiraterone acetate and prednisone per standard of care for at least 6 months in the absence of disease progression or unacceptable toxicity.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Antiandrogen Therapy
2015
Completed Phase 1
~10
Prednisone
2014
Completed Phase 4
~2370
Abiraterone Acetate
2015
Completed Phase 4
~1880
Radiation Therapy
2017
Completed Phase 3
~7250

Find a Location

Who is running the clinical trial?

University of WashingtonLead Sponsor
1,738 Previous Clinical Trials
1,844,381 Total Patients Enrolled
18 Trials studying Prostate Cancer
8,244 Patients Enrolled for Prostate Cancer
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,115 Total Patients Enrolled
561 Trials studying Prostate Cancer
507,173 Patients Enrolled for Prostate Cancer
Jing ZengPrincipal InvestigatorUniversity of Washington
7 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential risks have been observed with Abiraterone Acetate ingestion?

"Abiraterone acetate has been given a safety score of 2, as this is currently in its second phase trial. This means that while there are data sources to support the drug's security profile, efficacy has yet to be established."

Answered by AI

Could you provide a summary of the prior investigations related to Abiraterone Acetate?

"At present, the number of trials studying Abiraterone acetate is recorded at 368 with 100 studies in their terminal phase. Whereas Duarte, California holds most of these clinical trails for this medication, there are a total of 17429 sites across the US that have some form of trial running."

Answered by AI

What is the scope of individuals participating in this research?

"This trial is not currently accepting new participants. It was initially published on June 29th 2020, and the last update occurred on September 8th 2022. If you are seeking alternative trials, there are 5867 active cancer studies and 368 Abiraterone acetate investigations enrolling patients at this time."

Answered by AI

Are there any available opportunities to get involved in this research endeavor?

"This clinical trial, which was previously advertised on June 29th 2020 and most recently amended on September 8th 2022, is currently not recruiting. However, there are 6235 other medical studies actively looking for volunteers at this time."

Answered by AI

In what contexts has Abiraterone Acetate been demonstrated to be effective?

"Abiraterone acetate is primarily administered to patients with thyroiditis and can also be used for treating ulcerative colitis, malignant tumours, as well as varicella-zoster virus acute retinal necrosis."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer
Jing Zeng 2020. "Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03649841.
~2 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top