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Stem Cell Therapy

HB-adMSCs for Parkinson's Disease (PD Trial)

Phase 2
Waitlist Available
Led By Djamchid Lotfi, MD
Research Sponsored by Hope Biosciences Stem Cell Research Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to weeks 4, 8, 16, 24, 32, 42 and 52.
Awards & highlights

PD Trial Summary

This trial is designed to study whether multiple HB-adMSCs are safe and effective for treating Parkinson's disease. Up to 24 participants will be enrolled, and will be randomly assigned to receive either HB-adMSCs or placebo. The trial will last 32 weeks, with a follow-up period of 20 weeks after the last treatment.

PD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to weeks 4, 8, 16, 24, 32, 42 and 52.
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to weeks 4, 8, 16, 24, 32, 42 and 52. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
AEs of special interest (serious or non-serious) - hypersensitivities.
AEs of special interest (serious or non-serious) - infections
AEs of special interest (serious or non-serious) - thromboembolic events.
+14 more
Secondary outcome measures
Changes in Dosage of medications taken to treat Parkinson's disease.
Changes in MDS-UPDRS Part I.
Muscular Dystrophy
+31 more

PD Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: HB-adMSCsActive Control2 Interventions
Autologous Hope Biosciences adipose derived mesenchymal stem cells.
Group II: PlaceboPlacebo Group2 Interventions
Sterile Saline Solution 0.9%

Find a Location

Who is running the clinical trial?

Hope Biosciences Stem Cell Research FoundationLead Sponsor
21 Previous Clinical Trials
316 Total Patients Enrolled
Hope BiosciencesIndustry Sponsor
23 Previous Clinical Trials
302 Total Patients Enrolled
Djamchid Lotfi, MDPrincipal InvestigatorHope Biosciences Stem Cell Research Foundation
11 Previous Clinical Trials
84 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the investigators of this trial hoping to accomplish?

"The goal of this study is to assess vital signs over a 52-week period. Secondary outcomes include changes in the Unified Parkinson's disease Rating Scale (MDS-UPDRS), which includes assessments of motor function, speech, facial expression, rigidity, finger tapping, hand movements, pronation-supination movements of hands, toe tapping, leg agility, arising from chair, gait, freezing of gait, postural stability, posture, global spontaneity of movement (body bradykinesia), postural tremor of the hands kinetic tremor of the hands ,rest tremor amplitude constancy of"

Answered by AI

Are there any available positions for trial candidates?

"As of right now, this clinical trial is not looking for new patients. The 6/28/2021 post date was the start of the trial and 7/20/22 was the most recent update. There are 516 other trials currently underway for parkinson disease and 6 more that involve HB-adMSCs if you're interested in exploring additional research opportunities."

Answered by AI

Does my health profile fit the requirements for this experiment?

"This clinical trial is recruiting 24 participants with [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease) aged 18 to 75. Most importantly, patients are required to meet the following criteria:-Study participant is able and willing to comply with the requirements of this clinical trial.-Study participant must have been diagnosed with early and/or moderate Parkinson's disease at least 6 months before study participation.-Study participants should be able to read, understand and provide written consent.-Male and female participants 18 - 75 years of age.-Female study participants should not be pregnant or plan to become pregnant during study participation and for 6 months after last investigational product"

Answered by AI

Has a similar research project been conducted previously?

"Hope Biosciences sponsored the first trial for HB-adMSCs in 2020, which completed its Phase 1 & 2 drug approval stage that same year. Since then, 18297 studies have been completed. Currently, there are 6 live trials for HB-adMSCs across 4 cities and 1 countries."

Answered by AI

Are young adults eligible for this research program?

"Patients that meet the age requirements of 18-75 years old are eligible for this clinical trial. There are 28 other studies available for patients under 18 and 518 studies available for seniors above 65 years old."

Answered by AI

Are HB-adMSCs a new tool being trialed for treatment?

"There are six clinical trials currently underway that are studying the effects of HB-adMSCs. None of these studies have progressed to Phase 3 yet. Most of the research is taking place in Sugar Land, Texas; however, there are seven total locations running HB-adMSC clinical trials."

Answered by AI

What is the government's stance on HB-adMSCs?

"This Phase 2 trial has not yet demonstrated efficacy, but there is evidence that HB-adMSCs are safe. Therefore, we have rated it a 2."

Answered by AI

How many test subjects are included in the research?

"Currently, this trial is not recruiting patients. The study was first posted on June 28th 2021 and edited most recently on July 20th 2022. However, there are 516 trials for parkinson disease and 6 HB-adMSC studies that are actively recruiting participants."

Answered by AI
~6 spots leftby Apr 2025