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Non-steroidal Anti-inflammatory Drug

Indomethacin 100 mg rectally immediately after ERCP, NO prophylactic pancreatic stent placement for Pancreatitis (SVI Trial)

Phase 3

Waitlist Available

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up within 48 hours after ercp

Awards & highlights

SVI Trial Summary

This trial will test whether rectal indomethacin alone is non-inferior to the combination of rectal indomethacin and prophylactic pancreatic stent placement for preventing post-ERCP pancreatitis in high-risk cases.

Eligible Conditions

Post-ERCP Pancreatitis

SVI Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ within 48 hours after ercp

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~within 48 hours after ercp

This trial's timeline: 3 weeks for screening, Varies for treatment, and within 48 hours after ercp for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

The proportion of subjects in each study group with post-ERCP pancreatitis

Secondary outcome measures

The proportion of subjects in each study group with moderate-severe post-ERCP pancreatitis

SVI Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Indomethacin aloneExperimental Treatment1 Intervention

Indomethacin 100 mg rectally immediately after ERCP

Group II: Indomethacin+pancreatic stentActive Control1 Intervention

Indomethacin 100 mg rectally immediately after ERCP AND prophylactic pancreatic stent placement

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Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor

933 Previous Clinical Trials

7,392,685 Total Patients Enrolled

8 Trials studying Pancreatitis

1,641 Patients Enrolled for Pancreatitis

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH

2,359 Previous Clinical Trials

4,313,553 Total Patients Enrolled

26 Trials studying Pancreatitis

29,571 Patients Enrolled for Pancreatitis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In how many different medical institutions is this research project being conducted currently?

"There are 13 sites currently recruiting patients for this trial, which include major research universities such as Johns Hopkins University and the University of Michigan. Additionally, there are 10 other locations enrolling patients."

Answered by AI

Are any patients still needed for this clinical trial?

"This clinical trial is currently looking for patients, as reported on clinicaltrials.gov. Theclinical trial was initially posted on 9/1/2015 and was most recently edited on 6/25/2022."

Answered by AI

How many people are permitted to join this investigation?

"That is accurate, the clinical trial detailed on clinicaltrials.gov is recruiting patients as we speak. The listing was created on September 1st, 2015 and updated most recently on June 25th, 2022. They are looking for 2180 individuals total at 13 different locations."

Answered by AI