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Ultrasound-Guided Photodynamic Therapy for Pancreatic Cancer
Study Summary
This trial looks at whether a less invasive laser therapy, guided by ultrasound imaging, is as effective as current methods for treating patients with pancreatic cancer that has spread to other parts of the body.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- You have a condition called porphyria.You have a high level of difficulty performing everyday activities.You have a mental health condition that makes it hard to understand and agree to the study.You are older than 18 years.You have a history of serious bleeding or blood clotting issues and are currently taking medication to prevent blood clots.You have had another type of cancer that could affect how we check the response to the treatment.Your bilirubin levels are within a certain range, and you do not have an active, uncontrolled infection. If you are taking antibiotics, you can still participate.If you have cancer that has spread, it cannot have spread to certain places in the body. If the cancer has spread to the lungs, it cannot have more than three lesions, and none of the lesions can be larger than 5 cm.The cancer has spread to more than half of the duodenum or a major artery in the treatment area.You have been diagnosed with advanced or locally advanced pancreatic cancer or another solid pancreatic tumor that cannot be removed with surgery.You are allergic to contrast dye and cannot be treated with steroids and antihistamines.You have a tumor that can be measured using specific guidelines.You are expected to live for at least 12 more weeks.You are able to perform daily activities with little to no difficulty.
- Group 1: Treatment (verteporfin, EUS-guided PDT)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any current vacancies for this clinical trial?
"As of today, this clinical trial is still recruiting patients. The initial posting was on December 6th, 2016 with the most recent edit being made February 2nd, 2022."
Are there any other existing studies on Verteporfin's medical effects?
"At this time, there are five different clinical trials assessing the efficacy of Verteporfin. However, none of these studies have reached Phase 3. Many of theVerteporfin trials are being conducted in Winston-Salem, North carolina; however, research is also taking place at 10 other locations."
Does Verteporfin have any serious side effects?
"While there is some evidence to support the safety of Verteporfin, it only received a score of 2 because this medication has not yet been proven effective."
What is the total number of participants that will be included in this research?
"That is correct. The online information from clinicaltrials.gov indicates that this study, which was first posted on December 6th 2016, currently has open recruitment for 30 patients at 1 location."
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