Gabapentin for Azoospermia

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Azoospermia+2 More
Gabapentin - Drug
Eligibility
18+
Male
What conditions do you have?
Select

Study Summary

This trial is testing whether adding an anti-inflammatory to the usual painkillers given before, during, and after surgery will reduce pain and the need for narcotics afterwards.

Eligible Conditions
  • Azoospermia
  • Non-obstructive Azoospermia

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: Level of pain will be measured on day of surgery (Day 1), and post-operative days 1 through 7

Day 1
Change in narcotic consumption, as measured by duration of narcotic tablets consumption
Day 1
Change in narcotic consumption, as measured by frequency of narcotic tablets taken
Day 1
Change in Pain as measured by the NRS 1-11
Day 1
Change in narcotic consumption, as measured by number of tablets taken.

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Side Effects for

Gabapentin
2%Allergic reaction
This histogram enumerates side effects from a completed 2021 Phase 4 trial (NCT03012815) in the Gabapentin ARM group. Side effects include: Allergic reaction with 2%.

Trial Design

2 Treatment Groups

Gabapentin
1 of 2
Placebo
1 of 2
Experimental Treatment
Non-Treatment Group

68 Total Participants · 2 Treatment Groups

Primary Treatment: Gabapentin · Has Placebo Group · Phase 3

Gabapentin
Drug
Experimental Group · 1 Intervention: Gabapentin · Intervention Types: Drug
Placebo
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Gabapentin
FDA approved

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: level of pain will be measured on day of surgery (day 1), and post-operative days 1 through 7

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor
983 Previous Clinical Trials
1,337,984 Total Patients Enrolled
1 Trials studying Azoospermia
200 Patients Enrolled for Azoospermia
Nahid Punjani, M.D., M.P.H.Principal InvestigatorWeill Medical College of Cornell University
Caroline Kang, M.D.Principal InvestigatorWeill Medical College of Cornell University
Jessica Marinaro, M.D.Principal InvestigatorWeill Medical College of Cornell University

Eligibility Criteria

Age 18+ · Male Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have no contraindication to the consumption of gabapentin.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 17th, 2021

Last Reviewed: October 9th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.