Your session is about to expire
← Back to Search
Monoclonal Antibodies
Monoclonal Antibody Therapy for Ovarian Cancer
Phase 2
Waitlist Available
Research Sponsored by AltaRex
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Must have received only 1 prior platinum-based chemotherapy regimen
Cardiovascular: No uncontrolled hypertension, No congestive heart failure, No arrhythmias
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Study Summary
This trial is testing the effectiveness of monoclonal antibody therapy to treat ovarian, fallopian tube, or peritoneal cancer.
Who is the study for?
This trial is for adults with certain types of cancer (ovarian, fallopian tube, or peritoneal) who've had only one prior platinum-based chemo treatment. They should have no signs of current disease but a high CA 125 level and be expected to live at least another 6 months. People can't join if they're pregnant, have uncontrolled health issues like heart failure or hypertension, other cancers within the last 5 years (except some skin cancers), allergies to mouse proteins, or are on immunosuppressants.Check my eligibility
What is being tested?
The study is testing monoclonal antibody therapy's ability to target and kill cancer cells without harming normal ones in patients with specific gynecological cancers. It's a phase II trial where participants are randomly assigned to receive this treatment.See study design
What are the potential side effects?
Monoclonal antibody therapy might cause allergic reactions due to mouse proteins used in the drug development process. Other side effects could include fatigue, fever from infections since it affects the immune system, and potential anemia or low blood counts.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have had only one platinum-based chemotherapy treatment.
Select...
My blood pressure is controlled, and I don't have heart failure or irregular heartbeats.
Select...
My condition has not come back after treatment.
Select...
My cancer originates from the ovary, fallopian tube, or peritoneum.
Select...
My tests show no clear signs of disease.
Select...
My cancer is invasive and not considered low-grade.
Select...
I am 18 years old or older.
Select...
My bilirubin levels are not more than 1.5 times the normal range.
Select...
My creatinine level is 2 mg/dL or lower.
Select...
I am able to get out of my bed or chair and move around.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Find a Location
Who is running the clinical trial?
AltaRexLead Sponsor
1 Previous Clinical Trials
400 Total Patients Enrolled
1 Trials studying Ovarian Cancer
400 Patients Enrolled for Ovarian Cancer
Michael A. Bookman, MDStudy ChairFox Chase Cancer Center
1 Previous Clinical Trials
1 Trials studying Ovarian Cancer
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- It's been over 4 weeks since my last platinum-based chemotherapy, and I'm not on any chemotherapy now.My treatment plan does not specify endocrine therapy.I haven't had whole abdomen radiotherapy and it's been 6+ months since my last limited area radiotherapy.It has been over 4 weeks since my last surgery and I have not had my spleen removed.I have had only one platinum-based chemotherapy treatment.My blood pressure is controlled, and I don't have heart failure or irregular heartbeats.My condition has not come back after treatment.My cancer originates from the ovary, fallopian tube, or peritoneum.My tests show no clear signs of disease.My cancer is invasive and not considered low-grade.I am 18 years old or older.My bilirubin levels are not more than 1.5 times the normal range.My creatinine level is 2 mg/dL or lower.I have never received mouse-derived antibody treatments.I haven't taken any immunosuppressive or investigational drugs in the last 4 weeks.I am able to get out of my bed or chair and move around.
Research Study Groups:
This trial has the following groups:Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
In how many different geographical areas is this trial being run?
"At the moment, there are 16 sites conducting this study. They can be found in Newport Beach, Fort Myers, Indianapolis and other cities. If you wish to enroll in this trial, it may be beneficial for you to choose a site that is close to your location to reduce travel time and costs."
Answered by AI
Could you please list the risks associated with this treatment?
"As this is a Phase 2 trial, there is some data supporting safety but none verifying efficacy. Therefore, the Power team has given it a score of 2."
Answered by AI
Are there any patients who could still join this trial?
"No, this study is not currently recruiting patients. Although it was last updated on November 5th, 2013, the trial has been inactive for several years. There are, however, 715 other trials that may be of interest and are actively recruiting patients."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger