Bone Marrow Cells for Knee Osteoarthritis
(ACCELERATE3 Trial)
Trial Summary
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop taking your current medications, but it does mention that treatments like low dose Aspirin and Plavix are allowed. If you are on oral anticoagulants or heparin therapy, you may not be eligible to participate.
What data supports the effectiveness of the treatment Bone Marrow Aspirate Concentrate (BMAC) for knee osteoarthritis?
Is bone marrow aspirate concentrate (BMAC) safe for treating knee osteoarthritis?
How is the treatment Bone Marrow Aspirate Concentrate (BMAC) unique for knee osteoarthritis?
Bone Marrow Aspirate Concentrate (BMAC) is unique for knee osteoarthritis because it involves injecting a concentrate of bone marrow cells directly into the knee joint, which provides growth factors that help reduce inflammation and promote tissue repair. Unlike other treatments, BMAC uses the body's own cells to potentially improve joint function and alleviate symptoms.23678
What is the purpose of this trial?
The purpose of the ACCELERATE3 trial is to assess the efficacy of a single intra-articular (IA) injection of autologous BMAC, in one or both knees, compared to a single IA injection of Standard of Care (SOC) in patients with mild to severe knee OA.
Research Team
Riam Shamma, MD
Principal Investigator
CELL Technologies Inc.
Eligibility Criteria
This trial is for individuals with mild to severe knee osteoarthritis, which is a type of joint disease causing pain and stiffness. Participants will receive treatment in one or both knees.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single intra-articular injection of autologous BMAC or Standard of Care
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Bone Marrow Aspirate Concentrate (BMAC)
Find a Clinic Near You
Who Is Running the Clinical Trial?
CELL Technologies Inc.
Lead Sponsor