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Ketamine for Opioid Use Disorder and Depression
Study Summary
This trial seeks to evaluate whether ketamine can improve outcomes for people with opioid use disorder who are also struggling with depression.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 4 trial • 75 Patients • NCT03156504Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- I am between 18 and 65 years old.I have a health condition where a sudden rise in blood pressure could be harmful.I am between 18 and 65 years old.I have recently used prescribed or illicit benzodiazepines.I am between 18 and 65 years old.I am accepted into a methadone program for opioid or heroin addiction.My blood pressure is higher than 140/90 mmHg.I have had heart issues like a fast heartbeat or a heart attack.You use illegal drugs like opioids regularly.You have a serious addiction to opioids or heroin, as diagnosed by medical professionals.You use illegal drugs like opioids on a daily basis.
- Group 1: Ketamine
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research protocol available to participants at present?
"Affirmative. According to clinicaltrials.gov, this medical trial is actively seeking participants as of October 7th 2022 - the date that it was last updated. The initial posting on April 4th 2022 highlighted 6 enrollees needed at a single institution."
Is Ketamine Hydrochloride a viable option for individuals with no long-term risks?
"The safety of Ketamine Hydrochloride is rated as 2 since there has been some evidence to suggest it is safe but no data demonstrating its efficacy."
Is this clinical investigation open to elderly participants?
"As per the eligibility requirements, only individuals aged 18 or older but no more than 65 can enroll in this clinical trial."
How many research subjects are engaged in this investigation?
"Affirmative. Per the information on clinicaltrials.gov, this medical trial is actively searching for participants to join their research endeavour. This project was initially posted online on April 4th 2022 and has been freshly updated as of October 7th 2022. The team are seeking 6 volunteers at one facility in particular."
Do I qualify to partake in this experiment?
"This clinical trial is accepting 6 individuals, aged 18 to 65 years old, diagnosed with melancholia. Besides meeting the age criteria, potential participants must also meet certain prerequisites including: a history of illicit opioid use according to National Health Service (NHS) prescreening; fulfilment of DSM-5/ICD-10 criteria for moderate-to-severe opioid or heroin use disorder; acceptance into methadone maintenance care for treatment of opioid or heroin use disorder; 10 points on the PHQ-9 scale at screening stage and no prior sustained experience/dependence on ketamine as per responses in the respective questionnaire."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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