OFF stimulation followed by ON stimulation for Obsessive-Compulsive Disorder

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Obsessive-Compulsive Disorder+1 More
Deep brain stimulation - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Deep brain stimulation for treatment resistant deep brain stimulation

Eligible Conditions
  • Obsessive-Compulsive Disorder

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: 12 months

12 months
Obsessive compulsive symptoms as measured by the Yale-Brown Obsessive Compulsive Scale
Month 12
Quality of Life as measured by the Short-Form 36
Week 52
Obsessive compulsive symptoms as measured by the Yale-Brown Obsessive Compulsive Scale during randomization

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

OFF stimulation followed by ON stimulation
1 of 2
ON stimulation followed by OFF stimulation
1 of 2
Experimental Treatment

10 Total Participants · 2 Treatment Groups

Primary Treatment: OFF stimulation followed by ON stimulation · No Placebo Group · Phase 2

OFF stimulation followed by ON stimulation
Device
Experimental Group · 1 Intervention: Deep brain stimulation · Intervention Types: Device
ON stimulation followed by OFF stimulation
Device
Experimental Group · 1 Intervention: Deep brain stimulation · Intervention Types: Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Deep brain stimulation
2010
Completed Phase 3
~330

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months

Who is running the clinical trial?

Sunnybrook Health Sciences CentreLead Sponsor
598 Previous Clinical Trials
1,468,156 Total Patients Enrolled
8 Trials studying Obsessive-Compulsive Disorder
698 Patients Enrolled for Obsessive-Compulsive Disorder

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 26th, 2021

Last Reviewed: October 29th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.