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GLP-1 Receptor Agonist

Liraglutide for Childhood Obesity

Phase 2
Waitlist Available
Led By Ania Jastreboff, Phd,MD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Study Summary

This trial will study the effects of liraglutide, a medication used to treat obesity, on neural responses to HFCS in obese individuals.

Eligible Conditions
  • Neural Development
  • Childhood Obesity

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To investigate brain response in obese young adults who drink sugar sweetened beverages.
Secondary outcome measures
To investigate the effect of liraglutide on neural responses.
Other outcome measures
To investigate the role of specific metabolic/hormonal responses in the setting of liraglutide treatment, in affecting neural responses to sugar ingestion.

Side effects data

From 2017 Phase 4 trial • 100 Patients • NCT02014740
29%
nausea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Liraglutide
Metformin

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: obese subjectsExperimental Treatment1 Intervention
Subjects will self-administer Liraglutide once daily for 12 weeks.
Group II: lean subjectsActive Control1 Intervention
no intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Liraglutide
2013
Completed Phase 4
~2680

Find a Location

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,848 Previous Clinical Trials
2,737,804 Total Patients Enrolled
Ania Jastreboff, Phd,MDPrincipal InvestigatorYale University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have been recruited for this trial thus far?

"Unfortunately, this research has ceased patient recruitment. It had been posted on June 6th 2018 and was last updated November 1st 2021. For individuals looking for alternative studies, there are 1007 trials enrolling those with obesity and 35 related to Liraglutide actively recruiting participants."

Answered by AI

What potential adverse effects can patients expect from taking Liraglutide?

"Taking into consideration the fact that Liraglutide is in its second phase of clinical trials, our team at Power has assigned it a score of 2 for safety as there are some data points supporting safety but none to indicate efficacy."

Answered by AI

Are seniors, who are over 75 years of age, being invited to participate in this research?

"This clinical trial is selectively recruiting humans between the ages of 18 to 39. However, there are 256 trials for minors and 627 studies available for seniors 65 years old or above."

Answered by AI

Does this clinical research require any new participants at the present moment?

"This research project, which was initially posted on June 6th 2018 and last modified on November 1st 2021, is no longer seeking participants. Nonetheless, 1042 other clinical trials are accepting volunteers at this moment in time."

Answered by AI

What clinical applications does Liraglutide typically address?

"Liraglutide can be utilized to address physical exercise limitations, inadequate control with single-drug treatment plans, as well as reduce cardiovascular risk."

Answered by AI

Am I eligible to partake in this medical experiment?

"Those aged 18-39 and suffering from obesity are invited to participate in this medical trial. A number of prerequisites must be met by applicants, such as being right handed, possessing a baseline body mass index (BMI) between 18.5 and 45 kg/m2, maintaining weight stability, having the capacity for English literacy and consenting to written or verbal terms."

Answered by AI

Who else is applying?

What state do they live in?
New York
How old are they?
18 - 65
What site did they apply to?
Yale University
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.
2018. "Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03500484.
~2 spots leftby Apr 2025
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