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MET642 for Non-alcoholic Fatty Liver Disease

Phase 2
Waitlist Available
Research Sponsored by Metacrine, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 28 days after last dose
Awards & highlights

Study Summary

This study is evaluating whether a drug called MET642 can improve liver function in people with nonalcoholic steatohepatitis (NASH).

Eligible Conditions
  • Non-alcoholic Fatty Liver Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 28 days after last dose
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 28 days after last dose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adverse Events
ECG
Laboratory tests
+1 more
Secondary outcome measures
Pharmacodynamic Profile of MET642
Pharmacokinetic Profile of MET642
Pharmacological Activity of MET642

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: MET642 low doseExperimental Treatment1 Intervention
Group II: MET642 high doseExperimental Treatment1 Intervention
Group III: MET642 PlaceboPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MET642
2021
Completed Phase 2
~220

Find a Location

Who is running the clinical trial?

Metacrine, Inc.Lead Sponsor
1 Previous Clinical Trials
120 Total Patients Enrolled
1 Trials studying Non-alcoholic Fatty Liver Disease
120 Patients Enrolled for Non-alcoholic Fatty Liver Disease

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Study to Evaluate MET642 in Patients With NASH
2021. "Study to Evaluate MET642 in Patients With NASH". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04773964.
~53 spots leftby Apr 2025
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